COVID-19 vaccines and the virus: impact on drug metabolism and pharmacokinetics
ER McColl, MA Croyle, WC Zamboni, WG Honer… - Drug Metabolism and …, 2023 - ASPET
This article reports on an American Society of Pharmacology and Therapeutics, Division of
Drug Metabolism and Disposition symposium held at Experimental Biology on April 2, 2022 …
Drug Metabolism and Disposition symposium held at Experimental Biology on April 2, 2022 …
The impact of COVID-19 infection on cytochrome P450 3A4-mediated drug metabolism and drug interactions
S Villemure, SC Trenaman… - Expert Opinion on Drug …, 2023 - Taylor & Francis
SARS-CoV-2, the virus causing Coronavirus Disease 2019 (COVID-19), has given rise to a
global pandemic that has taken the lives of approximately 7 million individuals [1]. COVID-19 …
global pandemic that has taken the lives of approximately 7 million individuals [1]. COVID-19 …
Can COVID-19 have a clinically significant effect on drug metabolism?
F Ceban, M Subramaniapillai… - Expert Opinion on …, 2023 - Taylor & Francis
Hepatic metabolism is one of three major routes of drug elimination. Drug metabolism
generally involves a sequence of two reactions that allow for efficient excretion by the …
generally involves a sequence of two reactions that allow for efficient excretion by the …
Pharmacokinetic considerations to optimize clinical outcomes for COVID-19 drugs
CK Nwabufo, R Bendayan - Trends in Pharmacological Sciences, 2022 - cell.com
The development of clinically effective drugs that could complement existing vaccines is
urgently needed to reduce the morbidity and mortality associated with COVID-19. Drug …
urgently needed to reduce the morbidity and mortality associated with COVID-19. Drug …
[HTML][HTML] Immunomodulation may Affect the Efficacy of COVID-19 Medication by Changing Drug Metabolism and Pharmacokinetics
The COVID-19 outbreak, which was prompted by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) virus, continues to spread over the world. In the …
coronavirus 2 (SARS-CoV-2) virus, continues to spread over the world. In the …
Immunization and drug metabolizing enzymes: focus on hepatic cytochrome P450 3A
K Jonsson-Schmunk, R Ghose… - Expert review of …, 2021 - Taylor & Francis
Objective Infectious disease emergencies like the 2013–2016 Ebola epidemic and the 2009
influenza and current SARS-CoV-2 pandemics illustrate that vaccines are now given to …
influenza and current SARS-CoV-2 pandemics illustrate that vaccines are now given to …
Potential effects of COVID-19 on cytochrome P450-mediated drug metabolism and disposition in infected patients
S Deb, S Arrighi - European journal of drug metabolism and …, 2021 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been a global health crisis since it was
first identified in December 2019. In addition to fever, cough, headache, and shortness of …
first identified in December 2019. In addition to fever, cough, headache, and shortness of …
Cytochrome P450-mediated drug interactions in COVID-19 patients: Current findings and possible mechanisms
At the end of 2019, the entire world has witnessed the birth of a new member of coronavirus
family in Wuhan, China. Ever since, the Severe Acute Respiratory Syndrome Coronavirus 2 …
family in Wuhan, China. Ever since, the Severe Acute Respiratory Syndrome Coronavirus 2 …
Introduction to the mini special issue on next generation drug discovery and development: rethinking translational pharmacology for accelerated drug development
CK Nwabufo - Drug Metabolism Reviews, 2021 - Taylor & Francis
Abstract The coronavirus disease (COVID-19) pandemic further revealed the barriers to
accelerated discovery and development of transformative medicines for life threatening …
accelerated discovery and development of transformative medicines for life threatening …
Drug–drug interactions between COVID-19 therapeutics and antiretroviral treatment: the evidence to date
C Ellis, K Inaba, C Van de Vuurst… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction With new effective treatments for SARS-CoV-2, patient outcomes have greatly
improved. However, new medications bring a risk of drug interactions with other …
improved. However, new medications bring a risk of drug interactions with other …