Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …

Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …

Oxidative stress occurs early in the progression of Alzheimer disease, significantly before
the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. All …

Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …

Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …

Oxidative damage and inflammation are important features of the brain pathology of
Alzheimer's disease (AD). Oxidative damage can be found in membranes (lipid …

Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …

Multiple lines of evidence demonstrate that oxidative stress is an early event in Alzheimer's
disease (AD), occurring prior to cytopathology, and therefore may play a key pathogenic role …

Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …