[HTML][HTML] Inflammation-driven colorectal cancer associated with colitis: from pathogenesis to changing therapy

OM Nardone, I Zammarchi, G Santacroce, S Ghosh… - Cancers, 2023 - mdpi.com
Simple Summary Patients with inflammatory bowel disease (IBD) are at an increased risk of
developing colorectal cancer (CRC), mainly because of chronic intestinal inflammation …

[HTML][HTML] Inflammatory bowel disease and risk of colorectal cancer: An overview from pathophysiology to pharmacological prevention

M Lucafò, D Curci, M Franzin, G Decorti… - Frontiers in …, 2021 - frontiersin.org
Increased risk of colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients has
been attributed to long-standing chronic inflammation, with the contribution of genetic …

Molecular Pathways Underlying IBD-Associated Colorectal Neoplasia: Therapeutic Implications [RETRACTED]

GA Goel, A Kandiel, JP Achkar… - Official journal of the …, 2011 - journals.lww.com
Chronic inflammatory diseases, depending upon the duration and severity, are frequently
associated with an increased risk of developing cancer. A classic paradigm is the enhanced …

From inflammation to cancer in inflammatory bowel disease: molecular perspectives

M Romano, F De Francesco, L Zarantonello… - Anticancer …, 2016 - ar.iiarjournals.org
Inflammatory bowel diseases (IBD) are associated with an increased risk of colitis-
associated colorectal carcinoma (CAC). CAC is one of the most important causes of …

Advances in molecular mechanisms of inflammatory bowel disease‑associated colorectal cancer

Z Wang, Y Chang, H Sun, Y Li… - Oncology …, 2024 - spandidos-publications.com
The link between inflammation and cancer is well documented and colonic inflammation
caused by inflammatory bowel disease (IBD) is thought to be a high‑risk factor for the …

Colorectal cancer in inflammatory bowel disease: mechanisms and management

SC Shah, SH Itzkowitz - Gastroenterology, 2022 - Elsevier
Patients with inflammatory bowel disease (IBD) are at increased risk of developing
colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic …

[HTML][HTML] Update and latest advances in mechanisms and management of colitis-associated colorectal cancer

WY Dan, GZ Zhou, LH Peng, F Pan - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colitis-associated colorectal cancer (CAC) is defined as a specific cluster of colorectal
cancers that develop as a result of prolonged colitis in patients with inflammatory bowel …

[HTML][HTML] Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of …

H Zhang, Y Shi, C Lin, C He, S Wang, Q Li… - Frontiers in …, 2024 - frontiersin.org
Inflammatory bowel disease (IBD), characterized primarily by gastrointestinal inflammation,
predominantly manifests as Crohn's disease (CD) and ulcerative colitis (UC). It is …

From inflammation to colitis-associated colorectal cancer in inflammatory bowel disease: Pathogenesis and impact of current therapies

MC Fantini, I Guadagni - Digestive and Liver Disease, 2021 - Elsevier
The risk of colorectal cancer (CRC) is higher in patients with inflammatory bowel disease
(IBD). Population-based data from patients with ulcerative colitis (UC) estimate that the risk …

Inflammatory bowel disease and carcinogenesis

H Nagao-Kitamoto, S Kitamoto, N Kamada - Cancer and Metastasis …, 2022 - Springer
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer mortality worldwide. Colitis-associated colorectal cancer (CAC) is a subtype …