Chest computed tomography improvement in patients with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor: Early report
R Bec, M Reynaud-Gaubert, F Arnaud, R Naud… - European Journal of …, 2022 - Elsevier
Abstract Rationale and Objectives Cystic fibrosis transmembrane conductance regulator
(CFTR) modulators have revolutionised the treatment of cystic fibrosis (CF). Chest computed …
(CFTR) modulators have revolutionised the treatment of cystic fibrosis (CF). Chest computed …
Qualitative and quantitative evaluation of computed tomography changes in adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor: a retrospective …
S Dettmer, O Weinheimer, A Sauer-Heilborn… - Frontiers in …, 2023 - frontiersin.org
Introduction: The availability of highly effective triple cystic fibrosis transmembrane
conductance regulator (CFTR) modulator combination therapy with elexacaftor–tezacaftor …
conductance regulator (CFTR) modulator combination therapy with elexacaftor–tezacaftor …
Magnetic resonance imaging detects improvements of pulmonary and paranasal sinus abnormalities in response to elexacaftor/tezacaftor/ivacaftor therapy in adults …
L Wucherpfennig, SMF Triphan, S Wege… - Journal of Cystic …, 2022 - Elsevier
Abstract Background Therapy with Elexacaftor/Tezacaftor/Ivacaftor (ETI) was recently
approved for adult cystic fibrosis (CF) patients with at least one F508del mutation. However …
approved for adult cystic fibrosis (CF) patients with at least one F508del mutation. However …
Computed tomographic changes in patients with cystic fibrosis treated by combination therapy with lumacaftor and ivacaftor
F Arnaud, N Stremler-Le Bel… - Journal of Clinical …, 2021 - mdpi.com
Background: As Cystic Fibrosis (CF) treatments drastically improved in recent years, tools to
assess their efficiency need to be properly evaluated, especially cross-sectional imaging …
assess their efficiency need to be properly evaluated, especially cross-sectional imaging …
Early effects of elexacaftor-tezacaftor-ivacaftor therapy on magnetic resonance imaging in patients with cystic fibrosis and advanced lung disease
L Macconi, V Galici, M Di Maurizio, E Rossi… - Journal of Clinical …, 2022 - mdpi.com
This is a prospective, observational study involving three Cystic Fibrosis (CF) adult patients,
evaluating the changes in chest magnetic resonance imaging (MRI) three months after the …
evaluating the changes in chest magnetic resonance imaging (MRI) three months after the …
Long-term computed tomographic changes in cystic fibrosis patients treated with ivacaftor
G Chassagnon, D Hubert, I Fajac… - European …, 2016 - Eur Respiratory Soc
Cystic fibrosis (CF) patients with gating mutations in the gene coding for the CF
transmembrane conductance regulator (CFTR) protein have been the first to benefit from …
transmembrane conductance regulator (CFTR) protein have been the first to benefit from …
Impact of Elexacaftor–Tezacaftor–Ivacaftor on lung disease in cystic fibrosis
C Gushue, M Eisner, S Bai, T Johnson… - Pediatric …, 2023 - Wiley Online Library
Background In people with cystic fibrosis (pwCF), the impact of cystic fibrosis
transmembrane conductance regulator (CFTR) modulator therapies, such as Elexacaftor …
transmembrane conductance regulator (CFTR) modulator therapies, such as Elexacaftor …
[HTML][HTML] Measuring the effect of elexacaftor/tezacaftor/ivacaftor combination therapy on the respiratory pump in people with CF using dynamic chest radiography
Background The CFTR modulator elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) leads to
significant improvement in the symptoms and spirometry of people with cystic fibrosis …
significant improvement in the symptoms and spirometry of people with cystic fibrosis …
Dynamic perfluorinated gas MRI shows improved lung ventilation in people with cystic fibrosis after elexacaftor/tezacaftor/ivacaftor: an observational study
JL Goralski, SH Chung, AS Ceppe, MZ Powell… - Journal of Clinical …, 2022 - mdpi.com
The availability of highly effective CFTR modulators is revolutionizing the treatment of cystic
fibrosis (CF) and drastically improving outcomes. MRI-based imaging modalities are now …
fibrosis (CF) and drastically improving outcomes. MRI-based imaging modalities are now …
Lung Function in Patients with Cystic Fibrosis before and during CFTR-Modulator Therapy Using 3D Ultrashort Echo Time MRI
JF Heidenreich, PJ Kuhl, JP Grunz, R Hendel, C Metz… - Radiology, 2023 - pubs.rsna.org
Background The triple combination of the cystic fibrosis transmembrane regulator (CFTR)
modulators elexacaftor, tezacaftor, and ivacaftor (hereafter, elexacaftor/tezacaftor/ivacaftor) …
modulators elexacaftor, tezacaftor, and ivacaftor (hereafter, elexacaftor/tezacaftor/ivacaftor) …
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