Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Initiation and progression of atherosclerosis depend on local inflammation and
accumulation of lipids in the vascular wall. Although many cells are involved in the …

Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …

The presence of macrophages within the plaque is a defining hallmark of atherosclerosis.
Macrophages are exposed to various microenvironments such as oxidized lipids and …

Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages
play different and important roles. Phagocytic proinflammatory cells populate growing …

Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Atherosclerosis is an inflammatory disease caused by endothelial injury, lipid deposition,
and oxidative stress. This progressive disease can be converted into an acute clinical event …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

Macrophages orchestrate the inflammatory response in inflamed tissues, and recent work
indicates that these cells can alter their phenotypes and functions accordingly in response to …