Nanobiopsy: a tool for mitochondrial research

AG Bury - 2023 - theses.ncl.ac.uk
Understanding functional differences between mitochondrial subpopulations will help
improve our understanding of mitochondrial disease. Mitochondrial DNA heteroplasmy …

[HTML][HTML] Mitochondrial isolation: when size matters

AG Bury, AE Vincent, DM Turnbull, P Actis… - Wellcome open …, 2020 - ncbi.nlm.nih.gov
Mitochondrial vitality is critical to cellular function, with mitochondrial dysfunction linked to a
growing number of human diseases. Tissue and cellular heterogeneity, in terms of genetics …

Interrogating single cells

S Brown - Nature Nanotechnology, 2014 - nature.com
The ability to study the heterogeneous nature of cells in, for example, tumours has been
useful in gaining insights into cell–cell interactions and the pathology of disease at the …

Nanobiopsy investigation of the subcellular mtDNA heteroplasmy in human tissues

A Bury, A Pyle, AE Vincent, P Actis, G Hudson - Scientific Reports, 2024 - nature.com
Mitochondrial function is critical to continued cellular vitality and is an important contributor
to a growing number of human diseases. Mitochondrial dysfunction is typically …

Isolation of Mitochondria from Murine Skeletal Muscle

L Dong, X Li, A Li, J Yi, J Zhou - Methods in molecular …, 2024 - pubmed.ncbi.nlm.nih.gov
Skeletal muscle is one of the largest tissues in human body. Besides enabling voluntary
movements and maintaining body's metabolic homeostasis, skeletal muscle is also a target …

[PDF][PDF] Through the looking-glass: microscopy techniques for studying mitochondria

SDR Carrillo, N Street - 2022 - utupub.fi
Mitochondria are essential organelles of eukaryotic animal cells, representing the
powerhouses fueling all cellular processes. Despite their fundamental importance for …

Preparation of “functional” mitochondria: a challenging business

S Lehr, S Hartwig, J Kotzka - Mitochondrial Medicine: Volume I, Probing …, 2015 - Springer
As the powerhouse of the cell, mitochondria play a crucial role in many aspects of life,
whereby mitochondrial dysfunctions are associated with pathogenesis of many diseases …

Mitochondrial morphology and function in mitochondrial disease

J Faitg, T Davey, R Laws, C Lawless, H Tuppen… - bioRxiv, 2023 - biorxiv.org
Mitochondria play a crucial role in maintaining cellular health. It is interesting that the shape
of mitochondria can vary depending on the type of cell, mitochondrial function, and other …

A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics

JA MacDonald, AM Bothun, SN Annis… - Communications …, 2019 - nature.com
Mitochondria are well-characterized regarding their function in both energy production and
regulation of cell death; however, the heterogeneity that exists within mitochondrial …

Preparation of “functional” mitochondria: a challenging business

S Lehr, S Hartwig, J Kotzka - Mitochondrial Medicine: Volume 2 …, 2021 - Springer
As the powerhouse of the cell, mitochondria, plays a crucial role in many aspects of life,
whereby mitochondrial dysfunctions are associated with pathogenesis of many diseases …