The skeletal muscle is a dynamic organ composed of contractile muscle fibers, connective
tissues, blood vessels and nerve endings. Its main function is to provide motility to the body …

Sarcopenia is an age-related progressive loss of skeletal muscle mass, quality, and strength
disease. In addition, sarcopenia is tightly correlated with age-associated pathologies, such …

Skeletal muscle is essential for body physical activity, energy metabolism, and temperature
maintenance. It has excellent capabilities to maintain homeostasis and to regenerate after …

Muscle regeneration is a closely regulated process that involves a variety of cell types such
as satellite cells, myofibers, fibroadipogenic progenitors, endothelial cells, and inflammatory …

Skeletal muscle injury in aged rodents is characterized by an asynchronous infiltration of pro-
and anti-inflammatory macrophage waves, leading to improper and incomplete …

The purpose of this study was to test the hypothesis that macrophage polarization is altered
in old compared to young skeletal muscle, possibly contributing to the poor satellite cell …

Macrophages are one of the top players when considering immune cells involved with tissue
homeostasis. Recently, increasing evidence has demonstrated that macrophages could also …

Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to
raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a …

Aged skeletal muscle is characterized by poor muscle recovery following disuse coinciding
with an impaired muscle pro‐inflammatory macrophage response. Macrophage …

Aging is associated with diminished muscle mass, reductions in muscle stem cell functions,
and increased muscle fibrosis. The immune system, especially macrophages, can have …