Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
Background REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and
imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Casirivimab and imdevimab are non-competing monoclonal antibodies that
bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike …

REGEN-COV antibody combination and outcomes in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
Background In the phase 1–2 portion of an adaptive trial, REGEN-COV, a combination of the
monoclonal antibodies casirivimab and imdevimab, reduced the viral load and number of …

REGEN-COV antibody cocktail clinical outcomes study in Covid-19 outpatients

DM Weinreich, S Sivapalasingam, T Norton, S Ali… - MedRxiv, 2021 - medrxiv.org
Background REGEN-COV antibody cocktail (casirivimab with imdevimab) rapidly reduced
viral load and decreased medically-attended visits in the phase 1/2 portion of this trial; …

Casirivimab–Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19

RR Razonable, C Pawlowski, JC O'Horo, LL Arndt… - …, 2021 - thelancet.com
Background Real-world clinical data to support the use of casirivimab–imdevimab for the
treatment of outpatients with mild to moderate coronavirus disease-19 (COVID-19) is …

[HTML][HTML] Breakthrough COVID-19 and casirivimab-imdevimab treatment during a SARS-CoV-2 B1. 617.2 (Delta) surge

DM Bierle, R Ganesh, RR Razonable - Journal of Clinical Virology, 2021 - Elsevier
Introduction: The impact of vaccination and casirivimab-imdevimab monoclonal antibody
treatment on the clinical outcome of COVID-19 during a period of SARS-CoV-2 Delta surge …

Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: A randomised, double-blind, phase 3 trial

TL Holland, AA Ginde, R Paredes… - The Lancet …, 2022 - thelancet.com
Background Tixagevimab–cilgavimab is a neutralising monoclonal antibody combination
hypothesised to improve outcomes for patients hospitalised with COVID-19. We aimed to …

Real-world clinical outcomes of bamlanivimab and casirivimab-imdevimab among high-risk patients with mild to moderate coronavirus disease 2019

R Ganesh, LM Philpot, DM Bierle… - The Journal of …, 2021 - academic.oup.com
Background Bamlanivimab and casirivimab-imdevimab are authorized for treatment of mild
to moderate coronavirus disease 2019 (COVID-19) in high-risk patients. We compared the …

Casirivimab and imdevimab for the treatment of hospitalized patients with COVID-19

S Somersan-Karakaya, E Mylonakis… - The Journal of …, 2023 - academic.oup.com
Background The open-label RECOVERY study reported improved survival in hospitalized,
SARS-CoV-2 seronegative patients treated with casirivimab and imdevimab (CAS+ IMD) …

Effectiveness of regdanvimab treatment in high-risk COVID-19 patients to prevent progression to severe disease

JY Lee, JY Lee, JH Ko, M Hyun, HA Kim… - Frontiers in …, 2021 - frontiersin.org
Objective To evaluate clinical effectiveness of regdanvimab, a monoclonal antibody agent
for treating coronavirus 2019 (COVID-19). Methods A retrospective cohort study was …