Post‐hospitalization rehabilitation alleviates long‐term immune repertoire alteration in COVID‐19 convalescent patients

B Feng, D Zheng, L Yang, Z Su, L Tang, Y Zhu… - Cell …, 2023 - Wiley Online Library
The global pandemic of Coronavirus disease 2019 (COVID‐19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is an once‐in‐a‐lifetime public health …

Circulating Cytokines and Lymphocyte Subsets in Patients Who Have Recovered from COVID‐19

Hasichaolu, X Zhang, X Li, X Li… - BioMed research …, 2020 - Wiley Online Library
To investigate the immune status of people who previously had COVID‐19 infections, we
recruited two‐week postrecovery patients and analyzed circulating cytokine and lymphocyte …

Immune repertoire sequencing reveals an abnormal adaptive immune system in COVID‐19 survivors

C Jia, Z Zhou, W Pan, P Zhang, M Yang… - Journal of Medical …, 2023 - Wiley Online Library
Accumulating evidence suggests that severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2) impairs the adaptive immune system during acute infection. Still, it remains …

Alterations in T and B cell function persist in convalescent COVID-19 patients

HA Shuwa, TN Shaw, SB Knight, K Wemyss… - Med, 2021 - cell.com
Background Emerging studies indicate that some coronavirus disease 2019 (COVID-19)
patients suffer from persistent symptoms, including breathlessness and chronic fatigue; …

Long-Term Clinical Sequelae and Immunological Features of COVID-19 Survivors: A Cross-Sectional Study in Wuhan, China

D Zheng, L Zhang, B Feng, Y Liu, H Liu, J Hu, Q Lin… - 2021 - papers.ssrn.com
Objectives: To describe the clinical sequelae and immunological features of COVID-19
survivors who have been discharged from the hospital for 5-8 months. Methods: This study is …

Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients

CE Burnett, TLH Okholm, I Tenvooren, DM Marquez… - Immunity, 2022 - cell.com
While studies have elucidated many pathophysiological elements of COVID-19, little is
known about immunological changes during COVID-19 resolution. We analyzed immune …

[HTML][HTML] Persistent dysregulation of cellular immunity following COVID-19 recovery despite minimal post-COVID-19 sequelae manifestation

DU Putri, CK Huang, TY Ou, CF Lin, MC Lee… - The Journal of …, 2023 - ncbi.nlm.nih.gov
Most individuals affected by COVID-19 recovered uneventfully. However, mounting
evidence reported patients with persisting symptoms (post-COVID sequelae), 1 and …

Severe adaptive immune suppression may be why patients with severe COVID-19 cannot be discharged from the ICU even after negative viral tests

Y Zhou, X Liao, X Song, M He, F Xiao, X Jin… - Frontiers in …, 2021 - frontiersin.org
During the COVID-19 pandemic, a phenomenon emerged in which some patients with
severe disease were critically ill and could not be discharged from the ICU even though they …

Data-driven analysis of COVID-19 reveals persistent immune abnormalities in convalescent severe individuals

J Lim, KJ Puan, LW Wang, KWW Teng, CY Loh… - Frontiers in …, 2021 - frontiersin.org
Severe SARS-CoV-2 infection can trigger uncontrolled innate and adaptive immune
responses, which are commonly associated with lymphopenia and increased neutrophil …

SARS-CoV-2 immunity and functional recovery of COVID-19 patients 1-year after infection

Y Zhan, Y Zhu, S Wang, S Jia, Y Gao, Y Lu… - Signal transduction and …, 2021 - nature.com
The long-term immunity and functional recovery after SARS-CoV-2 infection have
implications in preventive measures and patient quality of life. Here we analyzed a …