Sarcopenia is a common skeletal muscle degenerative disease characterized by decreased
skeletal muscle mass and mitochondrial dysfunction that involves microRNAs (miR) as …

Sarcopenia is a common disorder that leads to a progressive decrease in skeletal muscle
function in elderly people. Exercise effectively prevents or delays the onset and progression …

Sarcopenia is a chronic degenerative disease affecting primarily older adults. A growing
aging population is gradually increasing the number of patients suffering from sarcopenia …

Obesity is a highly prevalent disease that can induce metabolic syndrome and is associated
with a greater risk of muscular atrophy. Mitochondria play central roles in regulating the …

The impairment of mitochondrial metabolism is a hallmark of aging. Mitonuclear imbalance
and the mitochondrial unfolded protein response (UPRmt) are two conserved mitochondrial …

Aim We examined the changes in oxidative stress, mitochondrial function and muscle
atrophy during aging in mice. Methods We used 6‐, 12‐and 24‐month (6 M, 12 M and 24 M) …

Background Exercise is an affordable and practical strategy to alleviate several detrimental
outcomes from the aging process, including sarcopenia. The elucidation of molecular …

Skeletal muscle aging is associated with a decline in motor function and loss of muscle
mass-a condition known as sarcopenia. The underlying mechanisms that drive this …

Purpose Lifelong exercise is known to attenuate sarcopenia (age-associated reduction in
muscle mass and function); however, the underlying molecular mechanisms remain unclear …

microRNAs (miRNAs) have been reported to be involved in many neurodegenerative
diseases. To explore the regulatory role of miR-34a in aging-related diseases such as …