Development of a vaccine against human cytomegalovirus: advances, barriers, and implications for the clinical practice

S Scarpini, F Morigi, L Betti, A Dondi, C Biagi, M Lanari - Vaccines, 2021 - mdpi.com
Human cytomegalovirus (hCMV) is one of the most common causes of congenital infection
in the post-rubella era, representing a major public health concern. Although most cases are …

Vaccine strategies against human cytomegalovirus infection

J Zhong, R Khanna - Expert Review of Anti-Infective Therapy, 2007 - Taylor & Francis
Human cytomegalovirus (HCMV) disease is a major cause of morbidity and mortality in
neonates and immunocompromised populations, such as transplant recipients and HIV …

Human cytomegalovirus vaccine: time to look for alternative options

R Khanna, DJ Diamond - Trends in molecular medicine, 2006 - cell.com
In 1999, the Institute of Medicine (IOM) of the National Academy of Sciences (USA) assigned
the highest priority for a vaccine to prevent congenital human cytomegalovirus (HCMV) …

Cytomegalovirus vaccine development

MR Schleiss - Human Cytomegalovirus, 2008 - Springer
Although infection with human cytomegalovirus (HCMV) is ubiquitous and usually
asymptomatic, there are individuals at high risk for serious HCMV disease. These include …

Update on the current status of cytomegalovirus vaccines

H Sung, MR Schleiss - Expert review of vaccines, 2010 - Taylor & Francis
Human cytomegalovirus (HCMV) is ubiquitous in all populations, and is the most commonly
recognized cause of congenital viral infection in developed countries. On the basis of the …

[HTML][HTML] Cytomegalovirus vaccines under clinical development

MR Schleiss - Journal of virus eradication, 2016 - Elsevier
Congenital cytomegalovirus (CMV) infection is the most common infectious cause of
disability in newborn infants. CMV also causes serious disease in solid organ (SOT) and …

Recent advances in designing an effective vaccine to prevent cytomegalovirus-associated clinical diseases

V Dasari, C Smith, R Khanna - Expert review of vaccines, 2013 - Taylor & Francis
It is now well over a decade since the US Institute of Medicine of the National Academy of
Sciences assigned the highest priority for a vaccine to prevent congenital human CMV …

A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection

CS Nelson, BC Herold, SR Permar - NPJ vaccines, 2018 - nature.com
Human cytomegalovirus (HCMV), a member of the beta-herpesvirus family, is the most
common cause of congenital infection worldwide as well as an important cause of morbidity …

Progress on pursuit of human cytomegalovirus vaccines for prevention of congenital infection and disease

TM Fu, Z An, D Wang - Vaccine, 2014 - Elsevier
Congenital infection of human cytomegalovirus (HCMV) is the leading cause of childhood
hearing loss and mental retardation. Unfortunately, a preventive vaccine remains elusive …

Desirability and feasibility of a vaccine against cytomegalovirus

P Griffiths, S Plotkin, E Mocarski, R Pass, M Schleiss… - Vaccine, 2013 - Elsevier
Publication of a report from the Institute of Medicine in 2000 showing that a vaccine against
cytomegalovirus (CMV) would likely be cost saving was very influential and encouraged the …