Using iterative pairwise external validation to contextualize prediction model performance: a use case predicting 1-year heart failure risk in patients with diabetes …

RD Williams, JM Reps, JA Kors, PB Ryan, E Steyerberg… - Drug Safety, 2022 - Springer
Introduction External validation of prediction models is increasingly being seen as a
minimum requirement for acceptance in clinical practice. However, the lack of …

Clinical Prediction Models for Heart Failure Hospitalization in Type 2 Diabetes: A Systematic Review and Meta‐Analysis

A Razaghizad, E Oulousian… - Journal of the …, 2022 - Am Heart Assoc
Background Clinical prediction models have been developed for hospitalization for heart
failure in type 2 diabetes. However, a systematic evaluation of these models' performance …

Machine learning to predict the risk of incident heart failure hospitalization among patients with diabetes: the WATCH-DM risk score

MW Segar, M Vaduganathan, KV Patel… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE To develop and validate a novel, machine learning–derived model to predict
the risk of heart failure (HF) among patients with type 2 diabetes mellitus (T2DM) …

Prognostic models for heart failure in patients with type 2 diabetes: a systematic review and meta-analysis

G Kostopoulos, I Doundoulakis, KA Toulis… - Heart, 2023 - heart.bmj.com
Objective To provide a systematic review, critical appraisal, assessment of performance and
generalisability of all the reported prognostic models for heart failure (HF) in patients with …

A risk prediction model for heart failure hospitalization in type 2 diabetes mellitus

BA Williams, D Geba, JM Cordova… - Clinical …, 2020 - Wiley Online Library
Background Antidiabetic therapies have shown disparate effects on hospitalization for heart
failure (HHF) in clinical trials. This study developed a prediction model for HHF in type 2 …

A machine learning approach identifies modulators of heart failure hospitalization prevention among patients with type 2 diabetes: a revisit to the ACCORD trial

H Kianmehr, J Guo, Y Lin, J Luo, W Cushman… - Journal of Diabetes and …, 2022 - Elsevier
Background To examine patient characteristics that may modulate the heterogeneous
treatment effect of intensive systolic blood pressure control (SBP) and intensive glycemic …

Development and validation of risk prediction equations to estimate future risk of heart failure in patients with diabetes: a prospective cohort study

J Hippisley-Cox, C Coupland - BMJ open, 2015 - bmjopen.bmj.com
Objective To develop and externally validate risk prediction equations to estimate the 10-
year risk of heart failure in patients with diabetes, aged 25–84 years. Design Cohort study …

Challenges and opportunities associated with incorporating new evidence of drug-mediated cardioprotection in the economic modeling of type 2 diabetes: a literature …

M Willis, C Asseburg, A Nilsson, C Neslusan - Diabetes Therapy, 2019 - Springer
Introduction Cardiovascular disease is a leading cause of mortality in people with type 2
diabetes mellitus (T2DM). Beginning in 2015, long-term cardiovascular outcomes trials …

Derivation and external validation of a clinical model to predict heart failure onset in patients with incident diabetes

LY Sun, SS Zghebi, AB Eddeen, PP Liu, DS Lee… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE Heart failure (HF) often develops in patients with diabetes and is recognized for
its role in increased cardiovascular morbidity and mortality in this population. Most existing …

[HTML][HTML] Evaluating the ability of economic models of diabetes to simulate new cardiovascular outcomes trials: a report on the ninth mount hood diabetes challenge

L Si, MS Willis, C Asseburg, A Nilsson, M Tew… - Value in Health, 2020 - Elsevier
Objectives The cardiovascular outcomes challenge examined the predictive accuracy of 10
diabetes models in estimating hard outcomes in 2 recent cardiovascular outcomes trials …