Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

AJ Grossberg, LC Chu, CR Deig… - CA: a cancer journal …, 2020 - Wiley Online Library
Despite tremendous gains in the molecular understanding of exocrine pancreatic cancer,
the prognosis for this disease remains very poor, largely because of delayed disease …

Pancreatic cancer: from bench to 5-year survival

J Kleeff, C Michalski, H Friess, MW Büchler - Pancreas, 2006 - journals.lww.com
Pancreatic ductal adenocarcinoma is one of the most aggressive human malignancies, with
an overall 5-year survival rate of less than 4%. On the molecular level, an increasing number …

[HTML][HTML] The current treatment paradigm for pancreatic ductal adenocarcinoma and barriers to therapeutic efficacy

DR Principe, PW Underwood, M Korc… - Frontiers in …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival
time of 10-12 months. Clinically, these poor outcomes are attributed to several factors …

Pancreatic cancer: why is it so hard to treat?

PE Oberstein, KP Olive - Therapeutic advances in …, 2013 - journals.sagepub.com
No common malignancy is as rapidly and inevitably fatal as pancreatic ductal
adenocarcinoma (PDA). This grim fact has driven substantial research efforts into this …

Advanced-stage pancreatic cancer: therapy options

J Werner, SE Combs, C Springfeld, W Hartwig… - Nature reviews Clinical …, 2013 - nature.com
Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, and surgical
resection is a requirement for a potential cure. However, the majority of patients are …

[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …

[HTML][HTML] Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment

PA Philip, M Mooney, D Jaffe, G Eckhardt… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer mortality,
despite significant improvements in diagnostic imaging and operative mortality rates. The 5 …

Pancreatic cancer

M Hidalgo - New England Journal of Medicine, 2010 - Mass Medical Soc
Deaths from pancreatic ductal adenocarcinoma, also known as pancreatic cancer, rank
fourth among cancer-related deaths in the United States, yet the causes of pancreatic cancer …

Pancreatic cancer–the past, the present, and the future

R Andersson, C Haglund, H Seppänen… - Scandinavian journal of …, 2022 - Taylor & Francis
Background Pancreatic cancer has been and still is associated with a very poor prognosis.
This is due to a lack of major breakthroughs with respect to early diagnosis, prognostication …

Pancreatic cancer: a review

W Park, A Chawla, EM O'Reilly - Jama, 2021 - jamanetwork.com
Importance Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer,
with approximately 60 430 new diagnoses expected in 2021 in the US. The incidence of …