How many cell types are in the kidney and what do they do?
The kidney maintains electrolyte, water, and acid-base balance, eliminates foreign and
waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 …
waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 …
The players: cells involved in glomerular disease
AR Kitching, HL Hutton - Clinical Journal of the American Society …, 2016 - journals.lww.com
Glomerular diseases are common and important. They can arise from systemic inflammatory
or metabolic diseases that affect the kidney. Alternately, they are caused primarily by local …
or metabolic diseases that affect the kidney. Alternately, they are caused primarily by local …
[HTML][HTML] Phenotypic diversity and metabolic specialization of renal endothelial cells
Complex multicellular life in mammals relies on functional cooperation of different organs for
the survival of the whole organism. The kidneys play a critical part in this process through …
the survival of the whole organism. The kidneys play a critical part in this process through …
Rationale and design of the kidney precision medicine project
Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous,
and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate …
and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate …
The glomerulus–a view from the inside–the endothelial cell
The glomerular endothelial cells are unique both in location and anatomy compared to most
other endothelial cells throughout the body. The absence of a diaphragm with retention of a …
other endothelial cells throughout the body. The absence of a diaphragm with retention of a …
Using single-cell technologies to map the human immune system—implications for nephrology
Advances in single-cell technologies are transforming our understanding of cellular identity.
For instance, the application of single-cell RNA sequencing and mass cytometry …
For instance, the application of single-cell RNA sequencing and mass cytometry …
[HTML][HTML] Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
Molecular characterization of the individual cell types in human kidney as well as model
organisms are critical in defining organ function and understanding translational aspects of …
organisms are critical in defining organ function and understanding translational aspects of …
[HTML][HTML] Kidney cells regeneration: dedifferentiation of tubular epithelium, resident stem cells and possible niches for renal progenitors
NV Andrianova, MI Buyan, LD Zorova… - International journal of …, 2019 - mdpi.com
A kidney is an organ with relatively low basal cellular regenerative potential. However, renal
cells have a pronounced ability to proliferate after injury, which undermines that the kidney …
cells have a pronounced ability to proliferate after injury, which undermines that the kidney …
Urinary single-cell profiling captures the cellular diversity of the kidney
Urinary Single-Cell Profiling Captures the Cellular Diversit... : Journal of the American Society
of Nephrology Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney …
of Nephrology Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney …
[HTML][HTML] Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing
A Schumacher, MB Rookmaaker, JA Joles… - NPJ Regenerative …, 2021 - nature.com
The kidney is among the most complex organs in terms of the variety of cell types. The
cellular complexity of human kidneys is not fully unraveled and this challenge is further …
cellular complexity of human kidneys is not fully unraveled and this challenge is further …