Circulating calprotectin as a biomarker of COVID-19 severity

M Mahler, PL Meroni, M Infantino… - Expert review of …, 2021 - Taylor & Francis
ABSTRACT Introduction Coronavirus disease 2019 (COVID-19) is an infectious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

[HTML][HTML] Calprotectin, an emerging biomarker of interest in COVID-19: a systematic review and meta-analysis

R Udeh, S Advani, LG de Guadiana Romualdo… - Journal of clinical …, 2021 - mdpi.com
COVID-19 has been shown to present with varied clinical course, necessitating a need for
more specific diagnostic tools that could identify severe cases and predict outcomes during …

[HTML][HTML] Serum calprotectin as a novel biomarker for severity of COVID-19 disease

T Kaya, S Yaylacı, A Nalbant, İ Yıldırım… - Irish Journal of Medical …, 2021 - Springer
Background Some biomarkers have been reported to be related to the prognosis of the
coronavirus disease 2019 (COVID-19). There are sparse data regarding the prognostic …

[HTML][HTML] Circulating levels of calprotectin, a signature of neutrophil activation in prediction of severe respiratory failure in COVID-19 patients: a multicenter, prospective …

L García de Guadiana-Romualdo… - Inflammation …, 2022 - Springer
Objective Severe COVID-19 is characterized by a dysregulated immune response in which
neutrophils play a critical role. Calprotectin reflects neutrophil activation and is involved in …

Neutrophil calprotectin identifies severe pulmonary disease in COVID-19

H Shi, Y Zuo, S Yalavarthi, K Gockman… - Journal of Leucocyte …, 2021 - academic.oup.com
Severe cases of coronavirus disease 2019 (COVID-19) are regularly complicated by
respiratory failure. Although it has been suggested that elevated levels of blood neutrophils …

Calprotectin: The link between acute lung injury and gastrointestinal injury in Covid-19: Ban or boon

HM Al-Kuraishy, AI Al-Gareeb… - Current Protein and …, 2022 - ingentaconnect.com
The pathogenesis of SARS-CoV-2 infection is related to the direct cytopathic effect and
associated hyper-inflammation due to exaggerated immune response. Different …

[HTML][HTML] Outcome prediction by serum calprotectin in patients with COVID-19 in the emergency department

W Bauer, E Diehl-Wiesenecker, J Ulke… - The Journal of …, 2021 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, becomes
clinically manifest in a broad range from mild symptoms to life-threatening multi-organ failure …

[HTML][HTML] Calprotectin and imbalances between acute-phase mediators are associated with critical illness in COVID-19

G Kassianidis, A Siampanos, G Poulakou… - International Journal of …, 2022 - mdpi.com
The trajectory from moderate and severe COVID-19 into acute respiratory distress syndrome
(ARDS) necessitating mechanical ventilation (MV) is a field of active research. We …

[HTML][HTML] Elevated fecal and serum calprotectin in COVID-19 are not consistent with gastrointestinal symptoms

H Shokri-Afra, A Alikhani, B Moradipoodeh… - Scientific reports, 2021 - nature.com
Intestinal epithelial cell damage caused by SARS-CoV-2 infection was thought to be
associated with gastrointestinal symptoms and decreased fecal consistency. The …

S100A8/A9 in COVID-19 pathogenesis: Impact on clinical outcomes

L Mellett, SA Khader - Cytokine & growth factor reviews, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) has a broad range of clinical manifestations,
highlighting the need for specific diagnostic tools to predict disease severity and improve …