[PDF][PDF] Evasion of type I interferon by SARS-CoV-2

H Xia, Z Cao, X Xie, X Zhang, JYC Chen, H Wang… - Cell reports, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) and spike (S) proteins antagonize host type I interferon response

Q Zhang, Z Chen, C Huang, J Sun, M Xue… - Frontiers in Cellular …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has spread worldwide and has infected more than 250 million …

[HTML][HTML] Activation and evasion of type I interferon responses by SARS-CoV-2

X Lei, X Dong, R Ma, W Wang, X Xiao, Z Tian… - Nature …, 2020 - nature.com
The pandemic of COVID-19 has posed an unprecedented threat to global public health.
However, the interplay between the viral pathogen of COVID-19, SARS-CoV-2, and host …

[HTML][HTML] Roles and functions of SARS-CoV-2 proteins in host immune evasion

F Rashid, Z Xie, M Suleman, A Shah, S Khan… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …

[HTML][HTML] Characterization of SARS-CoV-2 evasion: interferon pathway and therapeutic options

M Znaidia, C Demeret, S van der Werf, AV Komarova - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …

SARS-CoV-2 nonstructural protein 1 inhibits the interferon response by causing depletion of key host signaling factors

A Kumar, R Ishida, T Strilets, J Cole… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. While previous studies have …

[HTML][HTML] SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon

M Shemesh, TE Aktepe, JM Deerain, JL McAuley… - PLoS …, 2021 - journals.plos.org
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …

[HTML][HTML] Type I interferons in COVID-19 pathogenesis

E Palermo, D Di Carlo, M Sgarbanti, J Hiscott - Biology, 2021 - mdpi.com
Simple Summary The innate antiviral immune response is essential to limit virus replication
at early stages of infection, thus preventing viral spread and pathogenesis. Nevertheless …

Antagonism of type I interferon by severe acute respiratory syndrome coronavirus 2

H Xia, PY Shi - Journal of Interferon & Cytokine Research, 2020 - liebertpub.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), warranting urgent study of the molecular …

Interferon induction, evasion, and paradoxical roles during SARS‐CoV‐2 infection

C Chiale, TT Greene, EI Zuniga - Immunological Reviews, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of
coronavirus disease 2019 (COVID‐19), has caused millions of deaths in the past two years …