The evolution of human adiposity and obesity: where did it all go wrong?

JCK Wells - Disease models & mechanisms, 2012 - journals.biologists.com
Because obesity is associated with diverse chronic diseases, little attention has been
directed to the multiple beneficial functions of adipose tissue. Adipose tissue not only …

Aetiology of obesity: a striving after wind?

R Rosmond - Obesity reviews, 2004 - Wiley Online Library
The current global epidemic of obesity is fuelled by a constant, unidirectional adverse effect
on energy balance that exceeds the adaptive capacity of the system. The individual …

Obesity pathogenesis: an endocrine society scientific statement

MW Schwartz, RJ Seeley, LM Zeltser… - Endocrine …, 2017 - academic.oup.com
Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

Fat: an evolving issue

JR Speakman, S O'Rahilly - Disease models & mechanisms, 2012 - journals.biologists.com
Work on obesity is evolving, and obesity is a consequence of our evolutionary history. In the
space of 50 years, we have become an obese species. The reasons why can be addressed …

Deciphering adipose tissue heterogeneity

MD Lynes, YH Tseng - Annals of the New York Academy of …, 2018 - Wiley Online Library
Obesity is an excess accumulation of adipose tissue mass, and, together with its sequelae,
in particular type II diabetes and metabolic syndrome, obesity presents a major health crisis …

[图书][B] The evolutionary biology of human body fatness: thrift and control

JCK Wells - 2010 - books.google.com
This comprehensive synthesis of current medical and evolutionary literature addresses key
questions about the role body fat plays in human biology. It explores how body energy …

Adipose morphology and metabolic disease

P Tandon, R Wafer… - Journal of Experimental …, 2018 - journals.biologists.com
Adipose morphology is defined as the number and size distribution of adipocytes (fat cells)
within adipose tissue. Adipose tissue with fewer but larger adipocytes is said to have a …

[引用][C] The cause of obesity: are we barking up the wrong tree?

A Astrup, JO Hill, S Rössner - Obesity Reviews, 2004 - Wiley Online Library
Obesity may be more complex than most other societal problems we have faced so far.
Viewed from an energy balance viewpoint, obesity can be thought of as a failure of our …

Adipose tissue remodeling in pathophysiology of obesity

MJ Lee, Y Wu, SK Fried - Current Opinion in Clinical Nutrition & …, 2010 - journals.lww.com
Adipose tissue remodeling in pathophysiology of obesity : Current Opinion in Clinical
Nutrition & Metabolic Care Adipose tissue remodeling in pathophysiology of obesity …

The pathogenesis of obesity

LA Campfield, FJ Smith - Best practice & research Clinical endocrinology & …, 1999 - Elsevier
Obesity is an extremely challenging medical condition because it is a multifactorial disease
that lies at the interface between the biology of body energy regulation and an environment …