Assessment of neurotrophins and inflammatory mediators in vitreous of patients with diabetic retinopathy

JD Boss, PK Singh, HK Pandya, J Tosi… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To assess vitreous levels of inflammatory cytokines and neurotrophins (NTs) in
diabetic retinopathy (DR) and elucidate their potential roles. Methods: A prospective study …

Reduced levels of brain derived neurotrophic factor (BDNF) in the serum of diabetic retinopathy patients and in the retina of diabetic rats

MS Ola, MI Nawaz, AA El-Asrar, M Abouammoh… - Cellular and molecular …, 2013 - Springer
Diabetic retinopathy (DR) is widely recognized as a neurovascular disease. Retina, being a
neuronal tissue of the eye, produces neurotrophic factors for its maintenance. However …

Cytokine levels in human vitreous in proliferative diabetic retinopathy

DF Loporchio, EK Tam, J Cho, J Chung, GR Jun, W Xia… - Cells, 2021 - mdpi.com
In this study, we compare the vitreous cytokine profile in patients with proliferative diabetic
retinopathy (PDR) to that of patients without PDR. The identification of novel cytokines …

Profile of intraocular tumour necrosis factor‐α and interleukin‐6 in diabetic subjects with different degrees of diabetic retinopathy

C Gustavsson, CD Agardh, E Agardh - Acta ophthalmologica, 2013 - Wiley Online Library
Purpose: To assess and correlate the levels of inflammatory mediators in the eyes from non‐
diabetic and diabetic subjects without retinopathy (NDR), with non‐proliferative diabetic …

Inflammatory cytokines in vitreous fluid and serum of patients with diabetic vitreoretinopathy

T Yuuki, T Kanda, Y Kimura, N Kotajima… - Journal of Diabetes and …, 2001 - Elsevier
To determine whether inflammatory cytokines are increased in proliferative diabetic
retinopathy. We measured concentrations of interleukin-6, 8 (IL-6, 8) and tumor necrosis …

Concentration of haemodynamic and inflammatory related cytokines in diabetic retinopathy

JI Patel, GM Saleh, PG Hykin, ZJ Gregor, IA Cree - Eye, 2008 - nature.com
Aim There are changes in blood flow during the clinical stages of diabetic retinopathy with
increasing leukostasis and secondary elaboration of cytokines. This study evaluated the …

[HTML][HTML] Multiplex bead analysis of vitreous and serum concentrations of inflammatory and proangiogenic factors in diabetic patients

R Maier, M Weger, EM Haller-Schober… - Molecular …, 2008 - ncbi.nlm.nih.gov
Purpose To investigate the role of inflammatory and angiogenic factors in the pathogenesis
of diabetic retinopathy, we determined, in diabetic patients and controls, vitreous and serum …

[HTML][HTML] Multiplex bead array assay of plasma cytokines in type 2 diabetes mellitus with diabetic retinopathy

H Hang, S Yuan, Q Yang, D Yuan, Q Liu - Molecular vision, 2014 - ncbi.nlm.nih.gov
Purpose The aim of this study was to assess the roles of plasma cytokines in diabetic
retinopathy (DR) and their relationship with the severity of DR. Methods This study included …

Identification of VEGF-independent cytokines in proliferative diabetic retinopathy vitreous

JL Bromberg-White, L Glazer, R Downer… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: To identify inflammatory cytokines significantly elevated and independent of VEGF
levels in the vitreous of proliferative diabetic retinopathy (PDR) patients that may serve as …

Anti-inflammatory cytokine and angiogenic factors levels in vitreous samples of diabetic retinopathy patients

T Tsai, S Kuehn, N Tsiampalis, MK Vu, V Kakkassery… - PloS one, 2018 - journals.plos.org
Evaluation of cytokines in patients with diabetic retinopathy (DR) is important for the
identification of future additive or alternative treatment options. Therefore, vitreous samples …