Prostate cancer has become one of the most common tumors endangering men's health. At
present, the main clinical treatments for prostate tumors are surgery, radiotherapy, endocrine …

AIM: To explore the effect of microRNA-34a (miR-34a) on androgen receptor gene (AR)
targeting regulation and proliferation and apoptosis of prostate cancer (PCa) LNCaP cells …

Castration-resistant prostate cancer (CRPC), whose pathogenesis is known to be regulated
by microRNAs (miRNAs), has a poor prognosis. In our present study, we found that the …

Therapeutic targeting of p53 has been implicated as a promising strategy for cancer
treatment. MiRNAs are emerging as important modulators of invasion, regulation of p53 …

The main challenge in the treatment of prostate cancer (PCa) is that the majority of patients
inevitably develop resistance to androgen deprivation. However, the mechanisms involved …

Studies have shown that miR-221 and miR-222 are deregulated in many cancers, including
prostate cancer. Nevertheless, the biological role and the underlying mechanisms of miR …

Background: Prostate cancer (PCa) is a leading cause of tumor mortality in Western
societies. In China, the PCa mortality rate is increasing yearly. Androgen receptors (ARs) …

MicroRNAs have been implicated in regulating diverse cellular pathways. Emerging
evidence indicates that miR-143 plays causal roles in cancer tumorigenesis as a tumor …

Prostate cancer (PCa) is the most commonly diagnosed and secondly leading cause of
cancer death among males. But the precise mechanism of prostate cancer progression …

OBJECTIVE: To investigate the miR-296′ s function in prostate carcinoma (PCa) cells.
METHODS: In order to profile the miRNA expression in LNCaP cells, the cultured cells were …