Heparin (GAG-hed) inhibits LCR activity of human papillomavirus type 18 by decreasing AP1 binding

R Villanueva, N Morales-Peza, I Castelán-Sánchez… - BMC cancer, 2006 - Springer
Abstract Background High risk HPVs are causative agents of anogenital cancers. Viral E6
and E7 genes are continuously expressed and are largely responsible for the oncogenic …

Heparin increases the infectivity of H uman P apillomavirus T ype 16 independent of cell surface proteoglycans and induces L 1 epitope exposure

C Cerqueira, Y Liu, L Kühling, W Chai… - Cellular …, 2013 - Wiley Online Library
H uman P apillomaviruses (HPVs) are the etiological agents of cervical cancer, and HPV‐16
is the most prevalent type. Several HPVs require heparan sulfate proteoglycans (HSPGs) for …

Gallic acid induces apoptosis in human cervical epithelial cells containing human papillomavirus type 16 episomes

L Shi, Y Lei, R Srivastava, W Qin… - Journal of medical …, 2016 - Wiley Online Library
The high‐risk human papillomaviruses (HPV) that infect the anogenital tract are strongly
associated with the development of cervical carcinoma, which is the second most common …

Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment

MK Kim, HS Kim, SH Kim, JM Oh, JY Han… - Biochemical …, 2010 - Elsevier
Human papillomavirus (HPV) infection is considered to be the necessary cause of cervical
cancer. E6 and E7 oncoproteins of HPV have been known to play major roles in malignant …

Human papillomavirus type 16 oncoprotein E7 suppresses cadherin-mediated cell adhesion via ERK and AP-1 signaling

H Yuan, S Ito, T Senga, T Hyodo… - International …, 2009 - spandidos-publications.com
Human papillomaviruses (HPV) are the main etiological factor for cervical carcinoma. HPV-
16 is the most prevalent high-risk HPV-genotype found in HPV-associated cancers. We …

The human papillomavirus E6 and E7 inducible oncogene, hWAPL, exhibits potential as a therapeutic target

M Kuroda, T Kiyono, K Oikawa, K Yoshida… - British journal of …, 2005 - nature.com
Here we show that human papillomavirus (HPV) E6 and E7 oncoproteins induce hWAPL
expression. In addition, small interfering RNA (siRNA) of hWAPL suppressed the growth of …

Intracellular analysis of the interaction between the human papillomavirus type 16 E6 oncoprotein and inhibitory peptides

C Stutz, E Reinz, A Honegger, J Bulkescher… - PloS one, 2015 - journals.plos.org
Oncogenic types of human papillomaviruses (HPVs) cause cervical cancer and other
malignancies in humans. The HPV E6 oncoprotein is considered to be an attractive …

Human papillomavirus type 16 and 18 L1 protein peptide binding to VERO and HeLa cells inhibits their VLPs binding

R Vera‐Bravo, M Ocampo, M Urquiza… - … journal of cancer, 2003 - Wiley Online Library
Human papillomaviruses (HPVs) are the cause of epithelial lesions, HPV type 16 and type
18 being associated with the development of anogenital cancer. The L1 Major Capsid …

Inhibition of human papillomavirus DNA replication by an E1-derived p80/UAF1-binding peptide

M Lehoux, A Fradet-Turcotte, M Lussier-Price… - Journal of …, 2012 - Am Soc Microbiol
The papillomavirus E1 helicase is recruited by E2 to the viral origin, where it assembles into
a double hexamer that orchestrates replication of the viral genome. We previously identified …

Human papillomavirus replication regulation by acetylation of a conserved lysine in the E2 protein

Y Thomas, EJ Androphy - Journal of virology, 2018 - Am Soc Microbiol
The papillomavirus (PV) E2 protein is a sequence-specific DNA binding protein that recruits
cellular factors to its genome in infected epithelial cells. E2 also binds to and loads the viral …