[HTML][HTML] Killers 2.0: NK cell therapies at the forefront of cancer control

JJ Hodgins, ST Khan, MM Park… - The Journal of …, 2019 - Am Soc Clin Investig
Natural killer (NK) cells are innate cytotoxic lymphocytes involved in the surveillance and
elimination of cancer. As we have learned more and more about the mechanisms NK cells …

Harnessing natural killer cells for cancer immunotherapy: dispatching the first responders

NA Maskalenko, D Zhigarev… - Nature reviews Drug …, 2022 - nature.com
Natural killer (NK) cells have crucial roles in the innate immunosurveillance of cancer and
viral infections. They are 'first responders' that can spontaneously recognize abnormal cells …

[HTML][HTML] The application of natural killer cell immunotherapy for the treatment of cancer

K Rezvani, RH Rouce - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are essential components of the innate immune system and play a
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …

[HTML][HTML] NK cell-based cancer immunotherapy: from basic biology to clinical development

S Liu, V Galat, Y Galat4, YKA Lee… - Journal of hematology & …, 2021 - Springer
Natural killer (NK) cell is a specialized immune effector cell type that plays a critical role in
immune activation against abnormal cells. Different from events required for T cell activation …

[HTML][HTML] Natural killer cells: the linchpin for successful cancer immunotherapy

KA Shaver, TJ Croom-Perez, AJ Copik - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy is a highly successful and rapidly evolving treatment modality that
works by augmenting the body's own immune system. While various immune stimulation …

Roles of natural killer cells in immunity to cancer, and applications to immunotherapy

NK Wolf, DU Kissiov, DH Raulet - Nature Reviews Immunology, 2023 - nature.com
Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

Exploring the NK cell platform for cancer immunotherapy

JA Myers, JS Miller - Nature reviews Clinical oncology, 2021 - nature.com
Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that are
capable of killing virally infected and/or cancerous cells. Nearly 20 years ago, NK cell …

[HTML][HTML] Tumor-primed NK cells: waiting for the green light

M Sabry, MW Lowdell - Frontiers in Immunology, 2013 - frontiersin.org
The functional impairment of natural killer (NK) cells has been frequently reported in cancer
studies. As one of the central components of host anti-tumor immunity, NK cells exert cellular …

Boosting natural killer cell-based immunotherapy with anticancer drugs: a perspective

L Cifaldi, F Locatelli, E Marasco, L Moretta… - Trends in molecular …, 2017 - cell.com
Natural killer (NK) cells efficiently recognize and kill tumor cells through several mechanisms
including the expression of ligands for NK cell-activating receptors on target cells. Different …

Advantages and clinical applications of natural killer cells in cancer immunotherapy

E Ames, WJ Murphy - Cancer Immunology, Immunotherapy, 2014 - Springer
The past decade has witnessed a burgeoning of research and further insight into the biology
and clinical applications of natural killer (NK) cells. Once thought to be simple innate cells …