[HTML][HTML] Genetic risk, adherence to healthy lifestyle and acute cardiovascular and thromboembolic complications following SARS-COV-2 infection

J Xie, Y Feng, D Newby, B Zheng, Q Feng… - Nature …, 2023 - nature.com
Current understanding of determinants for COVID-19-related cardiovascular and
thromboembolic (CVE) complications primarily covers clinical aspects with limited …

[HTML][HTML] COVID-19 susceptibility variants associate with blood clots, thrombophlebitis and circulatory diseases

A Papadopoulou, H Musa, M Sivaganesan, D McCoy… - PLoS …, 2021 - journals.plos.org
Epidemiological studies suggest that individuals with comorbid conditions including
diabetes, chronic lung, inflammatory and vascular disease, are at higher risk of adverse …

Inherited Thrombophilias Are Associated With a Higher Risk of COVID-19–Associated Venous Thromboembolism: A Prospective Population-Based Cohort Study

H Stevens, R Canovas, H Tran, K Peter, JD McFadyen - Circulation, 2022 - Am Heart Assoc
The risk of venous thromboembolism (VTE) is markedly increased in patients with COVID-19
(COVID-19 VTE) and is associated with higher COVID-19 mortality. 1 Whether the presence …

[HTML][HTML] Genome-wide cross-trait analysis and Mendelian randomization reveal a shared genetic etiology and causality between COVID-19 and venous …

X Huang, M Yao, P Tian, JYY Wong, Z Li, Z Liu… - Communications …, 2023 - nature.com
Venous thromboembolism occurs in up to one-third of patients with COVID-19. Venous
thromboembolism and COVID-19 may share a common genetic architecture, which has not …

Analysis of genetic host response risk factors in severe COVID-19 patients

K Taylor, S Das, M Pearson, J Kozubek, M Pawlowski… - medRxiv, 2020 - medrxiv.org
ABSTRACT BACKGROUND Epidemiological studies indicate that as many as 20% of
individuals who test positive for COVID-19 develop severe symptoms that can require …

[HTML][HTML] Comorbidity genetic risk and pathways impact SARS-CoV-2 infection outcomes

RK Jaros, T Fadason, D Cameron-Smith, E Golovina… - Scientific Reports, 2023 - nature.com
Understanding the genetic risk and mechanisms through which SARS-CoV-2 infection
outcomes and comorbidities interact to impact acute and long-term sequelae is essential if …

A phenome‐wide investigation of risk factors for severe COVID‐19

A Baranova, H Cao, S Teng… - Journal of Medical …, 2023 - Wiley Online Library
With the continued spread of COVID‐19 globally, it is crucial to identify the potential risk or
protective factors associated with COVID‐19. Here, we performed genetic correlation …

Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19

JQ Xie, A Prats-Uribe, Q Feng, YH Wang… - JAMA internal …, 2022 - jamanetwork.com
Importance The risk of venous thromboembolism (VTE) in ambulatory COVID-19 is
controversial. In addition, the association of vaccination with COVID-19–related VTE and …

[HTML][HTML] Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality

T Nakanishi, S Pigazzini, F Degenhardt… - The Journal of …, 2021 - Am Soc Clin Investig
Background There is considerable variability in COVID-19 outcomes among younger adults,
and some of this variation may be due to genetic predisposition. Methods We combined …

[HTML][HTML] Associations between polygenic risk score and covid-19 susceptibility and severity across ethnic groups: UK Biobank analysis

R Farooqi, JS Kooner, W Zhang - BMC Medical Genomics, 2023 - Springer
Background COVID-19 manifests with huge heterogeneity in susceptibility and severity
outcomes. UK Black Asian and Minority Ethnic (BAME) groups have demonstrated …