Spatial transcriptomics data and analytical methods: an updated perspective

S Khan, JJ Kim - Drug Discovery Today, 2024 - Elsevier
Spatial transcriptomics (ST) is a newly emerging field that integrates high-resolution imaging
and transcriptomic data to enable the high-throughput analysis of the spatial localization of …

Deep learning in spatial transcriptomics: Learning from the next next-generation sequencing

AA Heydari, SS Sindi - Biophysics Reviews, 2023 - pubs.aip.org
Spatial transcriptomics (ST) technologies are rapidly becoming the extension of single-cell
RNA sequencing (scRNAseq), holding the potential of profiling gene expression at a single …

Spatial transcriptomics in human biomedical research and clinical application

W Hu, Y Zhang, J Mei, X Fang - Current Medicine, 2023 - Springer
Over the past 15 years, single-cell RNA sequencing (scRNA-seq) technology, in
combination with other omics, has revealed the mechanisms of human development …

Navigating the landscapes of spatial transcriptomics: How computational methods guide the way

R Li, X Chen, X Yang - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
Spatially resolved transcriptomics has been dramatically transforming biological and
medical research in various fields. It enables transcriptome profiling at single‐cell, multi …

Deep learning in spatial transcriptomics: Learning from the next next-generation sequencing

AA Heydari, SS Sindi - BioRxiv, 2022 - biorxiv.org
Spatial transcriptomics (ST) technologies are rapidly becoming the extension of single-cell
RNA sequencing (scRNAseq), holding the potential of profiling gene expression at a single …

Spatial transcriptomics in development and disease

R Zhou, G Yang, Y Zhang, Y Wang - Molecular Biomedicine, 2023 - Springer
The proper functioning of diverse biological systems depends on the spatial organization of
their cells, a critical factor for biological processes like shaping intricate tissue functions and …

[HTML][HTML] Spatial Transcriptomics: A Powerful Tool in Disease Understanding and Drug Discovery

J Cao, C Li, Z Cui, S Deng, T Lei, W Liu, H Yang… - Theranostics, 2024 - ncbi.nlm.nih.gov
Recent advancements in modern science have provided robust tools for drug discovery. The
rapid development of transcriptome sequencing technologies has given rise to single-cell …

A practical guide to spatial transcriptomics

L Valihrach, D Zucha, P Abaffy, M Kubista - Molecular Aspects of Medicine, 2024 - Elsevier
Spatial transcriptomics is revolutionizing modern biology, offering researchers an
unprecedented ability to unravel intricate gene expression patterns within tissues. From …

Spatial transcriptomics in neuroscience

N Jung, TK Kim - Experimental & Molecular Medicine, 2023 - nature.com
The brain is one of the most complex living tissue types and is composed of an exceptional
diversity of cell types displaying unique functional connectivity. Single-cell RNA sequencing …

Spatial transcriptomics: technical aspects of recent developments and their applications in neuroscience and cancer research

HE Park, SH Jo, RH Lee, CP Macks, T Ku… - Advanced …, 2023 - Wiley Online Library
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …