[HTML][HTML] CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways

SJ Ni, LQ Zhao, XF Wang, ZH Wu, RX Hua… - Journal of hematology & …, 2018 - Springer
Background Chromobox protein homolog 7 (CBX7), a member of the polycomb group (PcG)
family of proteins, is involved in the regulation of cell proliferation and cancer progression …

CBX3 promotes gastric cancer progression and affects factors related to immunotherapeutic responses

H Lin, J Lian, L Xia, G Guan, J You - Cancer management and …, 2020 - Taylor & Francis
Background Chromobox 3 (CBX3) is a member of the chromobox family proteins, which
plays a critical role in tumor progression, but the exact function of CBX3 in gastric cancer …

[HTML][HTML] Oncogenic role of the chromobox protein CBX7 in gastric cancer

XW Zhang, L Zhang, W Qin, XH Yao, LZ Zheng… - Journal of experimental …, 2010 - Springer
Abstract Background Chromobox 7 (CBX7) is a Polycomb family protein that extends the
lifespan of normal human cells via downregulating the expression of INK4a/ARF tumor …

CBX8 exhibits oncogenic activity via AKT/β-catenin activation in hepatocellular carcinoma

CZ Zhang, SL Chen, CH Wang, YF He, X Yang, D Xie… - Cancer research, 2018 - AACR
Deregulation of polycomb proteins influences the development and progression of
hepatocellular carcinoma. Here we show that chromobox 8 (CBX8) expression is increased …

[HTML][HTML] Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer

J Tang, G Wang, M Zhang, F Li, Y Sang, B Wang… - Oncotarget, 2014 - ncbi.nlm.nih.gov
The effect of polycomb chromobox (Cbx) proteins in cancer is context-dependent. The
Chromobox homolog 8 (CBX8) was originally characterized as a transcriptional repressor …

CBX4 exhibits oncogenic activities in breast cancer via Notch1 signaling

JS Zeng, ZD Zhang, L Pei, ZZ Bai, Y Yang… - The international journal …, 2018 - Elsevier
Polycomb chromobox (CBX) proteins are involved in gene silencing to function as
oncogenes or tumor suppressors through the polycomb repressive complex (PRC1). CBX4 …

[HTML][HTML] CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer

S Ni, H Wang, X Zhu, C Wan, J Xu, C Lu, L Xiao, J He… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Chromobox protein homolog 7 (CBX7), one of the polycomb group (PcG) proteins,
is a transcriptional repressor involved in the regulation of cell proliferation and senescence …

CBX4 promotes the proliferation and metastasis via regulating BMI‐1 in lung cancer

C Hu, Q Zhang, Q Tang, H Zhou, W Liu… - Journal of cellular …, 2020 - Wiley Online Library
Proliferation and metastasis are significantly malignant characteristics of human lung
cancer, but the underlying molecular mechanisms are poorly understood. Chromobox 4 …

[HTML][HTML] CBX2 depletion inhibits the proliferation, invasion and migration of gastric cancer cells by inactivating the YAP/β-catenin pathway

M Zeng, B Li, L Yang, Q Guan - Molecular medicine …, 2021 - spandidos-publications.com
Gastric cancer (GC) is the most common and fast‑growing malignancy of the digestive
system, which has a high mortality. Chromobox homolog 2 (CBX2) has been reported to be …

[HTML][HTML] CBX4 deletion promotes tumorigenesis under KrasG12D background by inducing genomic instability

F Chen, W Hou, X Yu, J Wu, Z Li, J Xu, Z Deng… - … and Targeted Therapy, 2023 - nature.com
Abstract Chromobox protein homolog 4 (CBX4) is a component of the Polycomb group
(PcG) multiprotein Polycomb repressive complexes 1 (PRC1), which is participated in …