[HTML][HTML] Cannabinoid delivery systems for pain and inflammation treatment

N Bruni, C Della Pepa, S Oliaro-Bosso, E Pessione… - Molecules, 2018 - mdpi.com
There is a growing body of evidence to suggest that cannabinoids are beneficial for a range
of clinical conditions, including pain, inflammation, epilepsy, sleep disorders, the symptoms …

[HTML][HTML] Cannabinoid formulations and delivery systems: Current and future options to treat pain

B Stella, F Baratta, C Della Pepa, S Arpicco, D Gastaldi… - Drugs, 2021 - Springer
The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

DP Finn, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021 - journals.lww.com
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Targeting cannabinoid agonists for inflammatory and neuropathic pain

Y Cheng, SA Hitchcock - Expert opinion on investigational drugs, 2007 - Taylor & Francis
The cannabinoid receptors CB1 and CB2 are class A G-protein-coupled receptors. It is well
known that cannabinoid receptor agonists produce relief of pain in a variety of animal …

Cannabinoid analgesia as a potential new therapeutic option in the treatment of chronic pain

TL Burns, JR Ineck - Annals of Pharmacotherapy, 2006 - journals.sagepub.com
Objective: To review the literature concerning the physiology of the endocannabinoid
system, current drug development of cannabinoid agonists, and current clinical research on …

The cannabinoid system and pain

SG Woodhams, V Chapman, DP Finn, AG Hohmann… - …, 2017 - Elsevier
Chronic pain states are highly prevalent and yet poorly controlled by currently available
analgesics, representing an enormous clinical, societal, and economic burden. Existing pain …

[HTML][HTML] The endocannabinoid system, cannabinoids, and pain

PG Fine, MJ Rosenfeld - Rambam Maimonides medical journal, 2013 - ncbi.nlm.nih.gov
The endocannabinoid system is involved in a host of homeostatic and physiologic functions,
including modulation of pain and inflammation. The specific roles of currently identified …

Cannabinoids in the management of difficult to treat pain

EB Russo - Therapeutics and clinical risk management, 2008 - Taylor & Francis
This article reviews recent research on cannabinoid analgesia via the endocannabinoid
system and non-receptor mechanisms, as well as randomized clinical trials employing …

[HTML][HTML] The endogenous cannabinoid system: a budding source of targets for treating inflammatory and neuropathic pain

G Donvito, SR Nass, JL Wilkerson, ZA Curry… - …, 2018 - nature.com
A great need exists for the development of new medications to treat pain resulting from
various disease states and types of injury. Given that the endogenous cannabinoid (that is …

Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes

J Manzanares, MD Julian… - Current …, 2006 - ingentaconnect.com
Cannabis extracts and synthetic cannabinoids are still widely considered illegal substances.
Preclinical and clinical studies have suggested that they may result useful to treat diverse …