Complex immunologic pathways, influenced by both genetic and environment triggers,
contribute to the development of atopic dermatitis and allergic contact dermatitis …

The prevalence of atopic dermatitis (AD) has increased markedly in the United States over
the past 5 decades, with current reports varying from 10% to 20% prevalence in US children …

The fundamental defect (s) that drives atopic dermatitis (AD) remains controversial.“Outside
in” proponents point to the important association of filaggrin gene mutations and other skin …

The pathophysiology of atopic dermatitis is complex and multifactorial, involving elements of
barrier dysfunction, alterations in cell mediated immune responses, IgE mediated …

Background: The relationship between atopic dermatitis and allergic contact dermatitis is
frequently debated, particularly in children. The impaired skin barrier of atopic subjects can …

Atopic dermatitis (AD) is a complex disease with multiple causes and complex mechanistic
pathways according to age of onset, severity of the illness, ethnic modifiers, response to …

Background Although atopic dermatitis (AD) often presents in infancy and persists into
adulthood, comparative characterization of AD skin among different pediatric age groups is …

Classic atopic dermatitis is complicated by asthma, allergic rhinitis, and food allergies,
cumulatively referred to as atopic diseases. Recent discoveries of mutations in the filaggrin …

Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder present in up to
20% of children. Recent advances implicate skin barrier dysfunction as central to disease …

Our understanding of the pathogenesis of atopic dermatitis has been dramatically enhanced
following the identification of the association with loss of function mutations in filaggrin, an …