SL Ginn, IE Alexander, ML Edelstein… - The journal of gene …, 2013 - Wiley Online Library
To date, over 1800 gene therapy clinical trials have been completed, are ongoing or have been approved worldwide. Our database brings together global information on gene therapy …
There have been many ups and downs since the introduction of gene therapy as a therapeutic modality for diseases. However, the journey of gene therapy has reached a …
ML Edelstein, MR Abedi, J Wixon - The Journal of Gene …, 2007 - Wiley Online Library
To date, over 1340 gene therapy clinical trials have been completed, are ongoing or have been approved worldwide. In 1997 we set up a database to bring together global …
E Hanna, C Rémuzat, P Auquier, M Toumi - Journal of market access & …, 2017 - mdpi.com
Background: In 1989, the concept of human gene therapies has emerged with the first approved human gene therapy trial of Rosenberg et al. Gene therapies are considered as …
ML Edelstein, MR Abedi, J Wixon… - The Journal of Gene …, 2004 - Wiley Online Library
In 1989, Rosenberg et al. performed the first human gene therapy trial when they used a retrovirus to introduce the gene coding for resistance to neomycin into human tumor …
Three decades of promise have culminated in the development of gene therapies that can be applied to a broad range of human diseases. After a brief history, we provide an overview …
26.2 Mavilio Commentary MH Page 1 NATURE|VOL 427|26 FEBRUARY 2004|www.nature.com/nature 779 in three patients. For the others, transplantation from mismatched donors carries a 75 …
XM Anguela, KA High - Annual review of medicine, 2019 - annualreviews.org
Gene therapies are gaining momentum as promising early successes in clinical studies accumulate and examples of regulatory approval for licensing increase. Investigators are …
The field of gene therapy is striving more than ever to define a path to the clinic and the market. Twenty gene therapy products have already been approved and over two thousand …