[HTML][HTML] Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications

Y Ye, Z Chen, S Jiang, F Jia, T Li, X Lu, J Xue… - Nature …, 2022 - nature.com
Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5+ DM) is
an autoimmune condition associated with rapidly progressive interstitial lung disease and …

Interstitial lung disease in anti-MDA5 positive dermatomyositis

W Wu, L Guo, Y Fu, K Wang, D Zhang, W Xu… - Clinical reviews in …, 2021 - Springer
Anti-melanoma differentiation-associated gene 5–positive dermatomyositis (MDA5+ DM) is
a rare autoimmune disease predominantly reported in East Asia. MDA5+ DM is an …

[HTML][HTML] Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry

P Mehta, PM Machado, L Gupta - Rheumatology International, 2021 - Springer
Abstract Anti-Melanoma Differentiation-Associated gene 5 (MDA-5) Dermatomyositis
(MDA5, DM) is a recently identified subtype of myositis characteristically associated with …

Identification of three different phenotypes in anti–melanoma differentiation–associated gene 5 antibody–positive dermatomyositis patients: implications for prediction …

L Xu, H You, L Wang, C Lv, F Yuan, J Li… - Arthritis & …, 2023 - Wiley Online Library
Objective There is substantial heterogeneity among the phenotypes of patients with anti–
melanoma differentiation–associated gene 5 antibody–positive (anti‐MDA5+) …

[HTML][HTML] Monoclonal antibodies from B cells of patients with anti-MDA5 antibody-positive dermatomyositis directly stimulate interferon gamma production

F Coutant, R Bachet, JJ Pin, M Alonzo… - Journal of Autoimmunity, 2022 - Elsevier
Anti-melanoma differentiation-associated gene 5 (MDA5) antibody (Ab) positive
dermatomyositis (anti-MDA5 DM) is a rare entity associated with poor prognosis and …

Anti-MDA5 antibody-positive dermatomyositis: pathogenesis and clinical progress

X Lu, Q Peng, G Wang - Nature Reviews Rheumatology, 2024 - nature.com
Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive
dermatomyositis (MDA5-DM) is a subtype of dermatomyositis. Although the aetiology and …

Anti–melanoma differentiation–associated protein 5–associated dermatomyositis: expanding the clinical spectrum

JC Hall, L Casciola‐Rosen, LA Samedy… - Arthritis care & …, 2013 - Wiley Online Library
Objective Autoantibodies against melanoma differentiation–associated protein 5 (MDA‐5)
have been described in several Asian dermatomyositis (DM) cohorts, often associated with …

[HTML][HTML] IFN-γ: An overlooked cytokine in dermatomyositis with anti-MDA5 antibodies

J Thuner, F Coutant - Autoimmunity Reviews, 2023 - Elsevier
Dermatomyositis with anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5
DM) is a rare autoimmune disease, often complicated by life-threatening, rapidly progressive …

[HTML][HTML] Dermatomyositis with anti-MDA5 antibodies: bioclinical features, pathogenesis and emerging therapies

A Nombel, N Fabien, F Coutant - Frontiers in immunology, 2021 - frontiersin.org
Anti-MDA5 dermatomyositis is a rare systemic autoimmune disease, historically described in
Japanese patients with clinically amyopathic dermatomyositis and life-threatening rapidly …

Clinical spectrum and therapeutics in Canadian patients with anti-melanoma differentiation-associated gene 5 (MDA5)-positive dermatomyositis: a case-based review

K Huang, O Vinik, K Shojania, J Yeung… - Rheumatology …, 2019 - Springer
The objective of the study was to determine the clinical features and treatment course in
Canadian patients with dermatomyositis (DM) associated with the anti-melanoma …