Objective: To examine the progress of positron emission tomography (PET) as a tool for
understanding the psychobiology of mood disorders, particularly major depression and …

Single photon emission computed tomography (SPECT) and positron emission tomography
(PET) studies are yielding a picture of clinical depression as a disorder associated with …

Converging clinical, biochemical, postmortem, and neuroimaging evidence suggests that
depression is unlikely to be a disease of a single brain region or neurotransmitter system …

Depressed individuals show impaired performance in tests of attention and concentration.
They also exhibit PET resting state abnormalities in dorsal prefrontal cortex and anterior …

Abstract to illustrate the types of experimental strategies that are useful in PET [positron
emission tomography] investigations of emotional disorders, we highlight our studies of …

Neuroimaging research has emerged as a valuable tool in shaping our understanding of the
pathophysiology of psychiatric disorders. We review functional neuroimaging findings …

Because anatomical studies of psychiatric disorders in humans have been largely
unsuccessful, and because pharmacological interventions in patients with mental illness can …

This report reviews six studies in which positron emission tomography (PET) was used to
investigate the neuroanatomic correlates of emotion, anxiety, and anxiety disorders. PET …

The functional neuroanatomy of unipolar major depression was investigated using positron
emission tomography to measure differences in regional cerebral blood flow (BF). A …

Several studies suggested the neural networks modulating aspects of emotional behaviour
to be implicated in the pathophysiology of mood disorders. These networks involve the …