Advances in attractive therapeutic approach for macrophage activation syndrome in COVID-19

S Chen, C Zhang, D Chen, L Dong, T Chang… - Frontiers in …, 2023 - frontiersin.org
Nowadays, people have relaxed their vigilance against COVID-19 due to its declining
infection numbers and attenuated virulence. However, COVID-19 still needs to be concern …

Macrophage activation syndrome and COVID-19

R Otsuka, K Seino - Inflammation and regeneration, 2020 - Springer
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating
pandemic. As we have not developed curative medicine and effective vaccine, the end of …

[HTML][HTML] Fatal gets more fatal: a COVID-19 infection with macrophage activation syndrome

Y Aydin, B Vemuri, JPV Gomez, PK Challa, H Zhang - Cureus, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) continues to be fatal despite advances in
the understanding of characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 …

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
The outbreak of new coronavirus disease-20119 or COVID-19 infection has become a
global health emergency at the beginning of this year. Currently, no specific vaccines and …

[HTML][HTML] Macrophage activation and cytokine release syndrome in COVID-19: current updates and analysis of repurposed and investigational anti-cytokine drugs

A Iqubal, F Hoda, AK Najmi, SE Haque - Drug Research, 2021 - thieme-connect.com
Coronavirus disease (COVID-19) emerged from Wuhan, has now become pandemic and
the mortality rate is growing exponentially. Clinical complication and fatality rate is much …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

[HTML][HTML] A case of delayed covid-19-related macrophage activation syndrome

A Abdelgabar, M Elsayed - Journal of Medical Cases, 2022 - ncbi.nlm.nih.gov
Abstract Although coronavirus disease 2019 (COVID-19) is primarily a respiratory illness,
clinical experiences have shown that almost no system is exempted. The severity of the …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …

Cytokines mediated hyperinflammation in SARS-CoV2: An Overview

L Ali - Life and Science, 2020 - ojs.lifenscience.org
Abstract Hyperinflammation induced by Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV2) is a major cause of disease severity and mortality in infected patients. The …

Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation

I Amigues, AH Pearlman, A Patel, P Reid… - Expert review of …, 2020 - Taylor & Francis
Introduction: The mortality of coronavirus disease 2019 (COVID-19) is frequently driven by
an injurious immune response characterized by the development of acute respiratory …