Recent steroid use and the relapse risk in ulcerative colitis patients with endoscopic healing

T Fukuda, H Yamazaki, Y Miyatani… - Alimentary …, 2024 - Wiley Online Library
Background Endoscopic healing (EH) is a therapeutic target in ulcerative colitis (UC).
However, even patients who have achieved EH relapse frequently. Aims To investigate the …

Complete histologic normalisation is associated with reduced risk of relapse among patients with ulcerative colitis in complete endoscopic remission

KC Cushing, W Tan, DH Alpers… - Alimentary …, 2020 - Wiley Online Library
Background Clinical and endoscopic remission are treatment targets in ulcerative colitis
(UC). The value of histologic healing in altering clinical outcomes among patients with …

Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis

S Ardizzone, A Cassinotti, P Duca, C Mazzali… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: It is uncertain whether mucosal healing after the first course of
corticosteroids therapy predicts outcome in patients with ulcerative colitis (UC). We …

Risk of relapse in patients with ulcerative colitis with persistent endoscopic healing: a durable treatment endpoint

S Jangi, AK Holmer, PS Dulai, BS Boland… - Journal of Crohn's …, 2021 - academic.oup.com
Background Deep remission in patients with UC has relied on initial achievement of
biochemical, endoscopic, and/or histological remission. We evaluated persistent …

Histologic remission does not offer additional benefit for ulcerative colitis patients in endoscopic remission

N Narula, A Aruljothy, AA Alshahrani… - Alimentary …, 2020 - Wiley Online Library
Background Histologic remission in ulcerative colitis (UC) patients may be associated with
positive outcomes. It is unclear whether UC patients in endoscopic remission obtain …

Endoscopic healing is associated with a reduced risk of biologic treatment failure in patients with ulcerative colitis

A Komatsu, T Toyonaga, N Sumiyoshi, M Tanaka… - Scientific Reports, 2024 - nature.com
Increasing number of patients with ulcerative colitis (UC) have received biologic treatment
during the last decade. The association between endoscopic healing (EH) and biologic …

Endoscopic and histological mucosal healing in ulcerative colitis in the first year of diagnosis: results from a population-based inception cohort from six countries in …

CM Leung, W Tang, M Kyaw, G Niamul… - Journal of Crohn's …, 2017 - academic.oup.com
Abstract Background and Aims Mucosal healing is associated with improved long-term
clinical outcomes in patients with ulcerative colitis. This population-based study assessed …

Predictors and outcomes of histological remission in ulcerative colitis treated to endoscopic healing

S Jangi, H Yoon, PS Dulai, M Valasek… - Alimentary …, 2020 - Wiley Online Library
Background Clinical remission is the recommended treatment target in ulcerative colitis. The
predictors and outcomes of achieving histologic remission within a treat‐to‐target paradigm …

Mucosal healing is associated with improved long-term outcomes of patients with ulcerative colitis: a systematic review and meta-analysis

SC Shah, JF Colombel, BE Sands, N Narula - Clinical gastroenterology and …, 2016 - Elsevier
Background & Aims The paradigm for treatment for ulcerative colitis (UC) is shifting from
resolving symptoms toward objective measures such as mucosal healing (MH). However, it …

Impact of histological and endoscopic remissions on clinical recurrence and recurrence-free time in ulcerative colitis

A Ponte, R Pinho, S Fernandes… - Inflammatory bowel …, 2017 - academic.oup.com
Background: Clinical and endoscopic remissions constitute the therapeutic goals in
ulcerative colitis (UC). Histological healing is currently not a target in UC. This study aims to …