[HTML][HTML] Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci

NI Strom, ZF Gerring, M Galimberti, D Yu… - medRxiv, 2024 - ncbi.nlm.nih.gov
Obsessive-compulsive disorder (OCD) affects~ 1% of the population and exhibits a high
SNP-heritability, yet previous genome-wide association studies (GWAS) have provided …

P462. Genome-Wide Association Study Identifies 15 Common Risk Variants Associated With Obsessive-Compulsive Disorder

N Strom, MW Halvorsen, C Rück… - Biological …, 2022 - biologicalpsychiatryjournal.com
Background To date, four genome-wide association studies (GWAS) of obsessive-
compulsive disorder (OCD) have been published, reporting a high heritability (SNP …

Genome-wide association study identifies new locus associated with OCD

NI Strom, D Yu, ZF Gerring, MW Halvorsen… - Medrxiv, 2021 - medrxiv.org
Obsessive-compulsive disorder (OCD) is a heritable disorder, but no definitive, replicated
OCD susceptibility loci have yet been identified by any genome-wide association study …

[HTML][HTML] Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population

NI Strom, CL Burton, C Iyegbe, T Silzer… - Molecular …, 2024 - nature.com
Abstract While 1–2% of individuals meet the criteria for a clinical diagnosis of obsessive-
compulsive disorder (OCD), many more (~ 13–38%) experience subclinical obsessive …

Genome-wide association study of obsessive-compulsive disorder

SE Stewart, D Yu, JM Scharf, BM Neale… - Molecular …, 2013 - nature.com
Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative …

Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis

D Posthuma - Molecular psychiatry, 2018 - research.vu.nl
Two obsessive-compulsive disorder (OCD) genome-wide association studies (GWASs)
have been published by independent OCD consortia, the International Obsessive …

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS

M Mattheisen, JF Samuels, Y Wang… - Molecular …, 2015 - nature.com
Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by intrusive
thoughts and urges and repetitive, intentional behaviors that cause significant distress and …

Identifying risk loci for obsessive-compulsive disorder and shared genetic component with schizophrenia: A large-scale multi-trait association analysis with summary …

J Dai, K Chen, Y Zhu, L Xia, T Wang, Z Yuan… - Progress in Neuro …, 2024 - Elsevier
Due to limited samples, no genetic loci have been identified for obsessive-compulsive
disorder (OCD) in genome-wide association studies. Additionally, although co-morbidities …

Genetic meta‐analysis of obsessive–compulsive disorder and self‐report compulsive symptoms

DJA Smit, D Cath, NR Zilhão, HF Ip… - American Journal of …, 2020 - Wiley Online Library
We investigated whether obsessive–compulsive (OC) symptoms from a population‐based
sample could be analyzed to detect genetic variants influencing obsessive–compulsive …

The polygenic risk for obsessive‐compulsive disorder is associated with the personality trait harm avoidance

K Bey, L Weinhold, R Grützmann… - Acta Psychiatrica …, 2020 - Wiley Online Library
Objective Obsessive‐compulsive disorder (OCD) is a complex psychiatric disorder with a
substantial genetic contribution. While the specific variants underlying OCD's heritability are …