Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti‐spike neutralizing IgG to SARS‐CoV‐2 variants, but preserved antigen …

B Beaton, SC Sasson, K Rankin… - American Journal of …, 2023 - Wiley Online Library
Patients with indolent lymphoma undertaking recurrent or continuous B cell suppression are
at risk of severe COVID‐19. Patients and healthy controls (HC; N= 13) received two doses of …

Humoral and cellular responses after a third dose of SARS-CoV-2 BNT162b2 vaccine in patients with lymphoid malignancies

D Re, B Seitz-Polski, V Brglez, M Carles… - Nature …, 2022 - nature.com
Patients with hematological malignancies have impaired immune response after two doses
of BNT162b2 (Pfizer/BioNTech) vaccine against SARS-CoV-2. Here, in this observational …

SARS‐CoV‐2 humoral responses following booster BNT162b2 vaccination in patients with B‐cell malignancies

E Terpos, D Fotiou, V Karalis… - American Journal of …, 2022 - Wiley Online Library
Patients with B‐cell malignancies have suboptimal immune responses to SARS‐CoV‐2
vaccination and are a high‐risk population for severe COVID19 disease. We evaluated the …

Anti-CD20 antibodies and bendamustine attenuate humoral immunity to COVID-19 vaccination in patients with B-cell non-Hodgkin lymphoma

T Ishio, S Tsukamoto, E Yokoyama, K Izumiyama… - Annals of …, 2023 - Springer
Serologic responses of COVID-19 vaccine are impaired in patients with B-cell lymphoma,
especially those who had recently been treated with anti-CD20 monoclonal antibodies …

Can B cell‐deficient patients rely on COVID‐19 vaccine‐induced T‐cell immunity?

T Shree - British Journal of Haematology, 2022 - Wiley Online Library
Anti‐CD20 antibody treatments prevent humoral responses to vaccines against severe
acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) vaccines, but the nature of T‐cell …

[HTML][HTML] Humoral serological response to the BNT162b2 vaccine is abrogated in lymphoma patients within the first 12 months following treatment with anti-CD2O …

R Gurion, U Rozovski, G Itchaki, A Gafter-Gvili… - …, 2022 - ncbi.nlm.nih.gov
Patients with lymphoma, especially those treated with anti-CD20 monoclonal antibodies,
suffer high COVID-19-associated morbidity and mortality. The goal of this study was to …

Impaired humoral responses to COVID-19 vaccination in patients with lymphoma receiving B-cell–directed therapies

P Ghione, JJ Gu, K Attwood, P Torka… - Blood, The Journal …, 2021 - ashpublications.org
Following a similar report on multiple myeloma, Ghione and colleagues report the expected
observation that patients with non-Hodgkin lymphoma (NHL) receiving anti-B cell therapies …

Cellular response to COVID-19 vaccines in hematologic malignancies patients: a new hope for non-responders?

I Saad Albichr, J De Greef, E Van Den Neste… - Leukemia & …, 2022 - Taylor & Francis
SARS-CoV-2 vaccines offered great hope in controlling the worldwide COVID-19 pandemic.
At present, SARS-CoV-2 vaccines have shown excellent efficacy to prevent COVID-19 but …

COVID-19 infection outcomes in patients receiving CD20 targeting T-cell engaging bispecific antibodies for B-cell non-Hodgkin lymphoma

VR Nachar, AJ Perissinotti, BL Marini, YH Karimi… - Annals of …, 2023 - Springer
Dear Editor, The increasing clinical data with BsAbs has highlighted their toxicity profile
including an alarming rate of COVID-19 and COVID-19 related infection and deaths [1–4] …

BNT162b2 COVID‐19 vaccine is significantly less effective in patients with hematologic malignancies

K Herzog Tzarfati, O Gutwein, A Apel… - American Journal of …, 2021 - Wiley Online Library
Patients with hematologic malignancies have an increased risk of severe COVID‐19
infection. Vaccination against COVID‐19 is especially important in these patients, but …