Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post‐acute sequelae of COVID‐19

C Schultheiß, E Willscher, L Paschold… - Journal of Medical …, 2023 - Wiley Online Library
Post‐acute sequelae of COVID‐19 (PASC) are long‐term consequences of SARS‐CoV‐2
infection that can substantially impair the quality of life. Underlying mechanisms ranging …

Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae

Z Swank, Y Senussi, G Alter, DR Walt - Medrxiv, 2022 - medrxiv.org
The diagnosis and management of post-acute sequelae of COVID-19 (PASC) poses an
ongoing medical challenge. Identifying biomarkers associated with PASC would immensely …

Plasma biomarkers for systemic inflammation in COVID‐19 survivors

J Zhao, M Schank, L Wang, X Dang… - PROTEOMICS …, 2022 - Wiley Online Library
Background While the majority of COVID‐19 patients fully recover from the infection and
become asymptomatic, a significant proportion of COVID‐19 survivors experience a broad …

Long-term elevated inflammatory protein levels in asymptomatic SARS-CoV-2 infected individuals

L Tserel, P Jõgi, P Naaber, J Maslovskaja… - Frontiers in …, 2021 - frontiersin.org
The clinical features of SARS-CoV-2 infection range from asymptomatic to severe disease
with life-threatening complications. Understanding the persistence of immune responses in …

Persistent serum protein signatures define an inflammatory subcategory of long COVID

A Talla, SV Vasaikar, GL Szeto, MP Lemos… - Nature …, 2023 - nature.com
Long COVID or post-acute sequelae of SARS-CoV-2 (PASC) is a clinical syndrome featuring
diverse symptoms that can persist for months following acute SARS-CoV-2 infection. The …

[HTML][HTML] 'The long tail of Covid-19'-The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients

I Doykov, J Hällqvist, KC Gilmour, L Grandjean… - …, 2020 - ncbi.nlm.nih.gov
Abstract 'Long Covid', or medical complications associated with post SARS-CoV-2 infection,
is a significant post-viral complication that is being more and more commonly reported in …

Serological response to vaccination in post-acute sequelae of COVID

S Joung, B Weber, M Wu, Y Liu, AB Tang… - BMC Infectious …, 2023 - Springer
Background Individuals with post-acute sequelae of COVID (PASC) may have a persistence
in immune activation that differentiates them from individuals who have recovered from …

Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection

FJ Ryan, CM Hope, MG Masavuli, MA Lynn… - BMC medicine, 2022 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …

[HTML][HTML] A multi-omics based anti-inflammatory immune signature characterizes long COVID-19 syndrome

JJ Kovarik, A Bileck, G Hagn, SM Meier-Menches… - Iscience, 2023 - cell.com
To investigate long COVID-19 syndrome (LCS) pathophysiology, we performed an
exploratory study with blood plasma derived from three groups: 1) healthy vaccinated …

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

AD Proal, MB VanElzakker, S Aleman, K Bach… - Nature …, 2023 - nature.com
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …