AI analysis of chest radiographs as a biomarker of biological age

PS Babyn, SJ Adams - The Lancet Healthy Longevity, 2023 - thelancet.com
Chronological age is the greatest risk factor for most common chronic diseases. However,
molecular and cellular age-related decline varies substantively between individuals …

An interpretable biological age

Q Zhang - The Lancet Healthy Longevity, 2023 - thelancet.com
Biological age as an integrated value of biophysiological measures has been widely
investigated as a biomarker of ageing. It outperforms chronological age in predicting the …

Redefining age-based screening and diagnostic guidelines: an opportunity for biological aging clocks in clinical medicine?

JC Nwanaji-Enwerem, WB Mair - The Lancet Healthy Longevity, 2022 - thelancet.com
Clinicians often note that patients seem older or younger than their stated age to convey
their appraisal of a patient's biological or physiological age and subsequent disease risks …

Chest radiography as a biomarker of ageing: artificial intelligence-based, multi-institutional model development and validation in Japan

Y Mitsuyama, T Matsumoto, H Tatekawa… - The Lancet Healthy …, 2023 - thelancet.com
Background Chest radiographs are widely available and cost-effective; however, their
usefulness as a biomarker of ageing using multi-institutional data remains underexplored …

Advanced pathological ageing should be represented in the ICD

E Bischof, AB Maier, KF Lee, A Zhavoronkov… - The Lancet Healthy …, 2022 - thelancet.com
The rapidly evolving field of longevity medicine focuses on identifying individual ageing
trajectories by determining the biological age over time and targeting ageing mechanisms to …

The Aging Biomarker Consortium represents a new era for aging research in China

J Ren, M Song, W Zhang, JP Cai, F Cao, Z Cao… - Nature Medicine, 2023 - nature.com
The global population of older peo-ple is growing at an unprecedented rate, with the number
of people over 65 years of age expected to reach 1.6 billion by 2050. Given that aging is a …

Why we need ageing research sensitive to age and gender

S Oertelt-Prigione - The Lancet Healthy Longevity, 2021 - thelancet.com
I work in the field of sex-sensitive and gender-sensitive medicine, and I am frequently asked
why my colleagues and I worry so much about women, given that they outlive men almost …

Not a disease: a global call for action urging revision of the ICD-11 classification of old age

D Banerjee, S Mukhopadhyay, K Rabheru… - The Lancet Healthy …, 2021 - thelancet.com
The inclusion of old age in the 11th revision of the International Classification of Diseases
(ICD-11) under general symptoms (code MG2A) and in the causality section of XT9T, 1 has …

Alzheimer's disease risk biomarkers: progress and challenges

PB Adkins-Jackson, DW Belsky - The Lancet Healthy Longevity, 2022 - thelancet.com
Alzheimer's disease and Alzheimer's disease-related dementias (AD–ADRD) are
progressive neurodegenerative conditions that occur more frequently in older adults. As …

Age-related disease burden as a measure of population ageing

DS Kehler - The Lancet Public Health, 2019 - thelancet.com
Improvements in health care and social circumstances have resulted in people living longer.
Still, not all people thrive in good health as they age: the oldest old might be long lived but …