Parkinson's disease is a genetically complex disorder. Multiple genes have been shown to
contribute to the risk of Parkinson's disease, and currently 90 independent risk variants have …

Objective To determine if any association between previously identified alleles that confer
risk for Parkinson disease and variables measuring disease progression. Methods We …

Background: Mutations in GBA and LRRK2 genes have been implicated in Parkinson
disease (PD), particularly in Ashkenazi Jews. Methods: An Israeli Ashkenazi cohort of 420 …

Objective Coding variants in the GBA gene have been identified as the numerically most
important genetic risk factors for Parkinson's disease (PD). In addition, genome-wide …

Multiple genetic variants have been linked to risk of Parkinson disease (PD), but known
mutations do not explain a large proportion of the total PD cases. Similarly, multiple loci …

Background: Numerous studies have indicated that there is a possible relationship between
GBA variants and Parkinson's disease (PD), however, most of them focused on a few …

Introduction Variants in the GBA1 gene have been identified as a common risk factor for
Parkinson's disease (PD). In addition to pathogenic mutations (those associated with …

Objective To provide a variant-specific estimate of incidence, penetrance, sex distribution,
and association with dementia of the 4 most common Parkinson disease (PD)-associated …

Objectives: Mutations in the GBA gene occur in 7% of patients with Parkinson disease (PD)
and are a well-established susceptibility factor for PD, which is characterized by Lewy body …

Background An understanding of the genetic mechanisms underlying diseases in
ancestrally diverse populations is an important step towards development of targeted …