Multidimensional pan-cancer analysis of HSPA5 and its validation in the prognostic value of bladder cancer

YX Wang, J Wang, Y Liu, XL Wang, MH Ren - Heliyon, 2024 - cell.com
Endoplasmic reticulum (ER) stress-related genes are closely related to the occurrence,
development, and immunotherapy response of tumors. This study provides a …

A pan-cancer analysis to determine the prognostic analysis and immune infiltration of HSPA5

RK Zhu, W Zhang, YX Zhang… - Current cancer drug …, 2024 - ingentaconnect.com
Background: Heat shock 70kDa protein 5 (HSPA5), also known as GRP78, is widely
expressed in most malignant cells and has been shown to have a significant role in the …

Predictive Value and Immunological Role of the HSPA5 Gene in Cervical Cancer

Y Bai, Y Miao, J Wang, J Gan, J Feng - Biochemical Genetics, 2024 - Springer
Cervical cancer (CC) ranks fourth among women's malignancies worldwide and seriously
affects women's health. HSPA5 is a heat shock protein, also known as glucose regulatory …

HSPA5 promotes the proliferation, metastasis and regulates ferroptosis of bladder cancer

Q Wang, S Ke, Z Liu, H Shao, M He, J Guo - International Journal of …, 2023 - mdpi.com
Heat shock protein family A (HSP70) member 5 (HSPA5) is aberrantly expressed in various
tumors and closely associated with the progression and prognosis of cancer. Nevertheless …

[HTML][HTML] A human pan-cancer system analysis of heat shock protein family A member 5

C Deng, S Gong, L Lin, J Tang, X Pang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Heat shock protein family A member 5 (HSPA5) plays a pivotal role in the endoplasmic
reticulum (ER) stress response and unfolded protein response (UPR), both of which are …

Significant correlation between HSPA4 and prognosis and immune regulation in hepatocellular carcinoma

BB Shang, J Chen, ZG Wang, H Liu - PeerJ, 2021 - peerj.com
Background Hepatocellular carcinoma (HCC) is an inflammation-associated tumor involved
in immune tolerance and evasion in the immune microenvironment. Heat shock proteins …

[HTML][HTML] Unveiling the potential of HSPA4: a comprehensive pan-cancer analysis of HSPA4 in diagnosis, prognosis, and immunotherapy

J Yang, X Wu, J You - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
With the global rise in cancer incidence and mortality rates, research on the topic has
become increasingly urgent. Among the significant players in this field are heat shock …

High Expression of HSPA8 Is A Favorable Prognostic Factor in Colon Cancer

Y Liu, X He - 2021 - researchsquare.com
Background: Colon adenocarcinoma (COAD), a type of colon cancer, is among the most
common malignant diseases afflicting people globally. Heat shock protein family, including …

Pseudogene HSPA7 is a poor prognostic biomarker in Kidney Renal Clear Cell Carcinoma (KIRC) and correlated with immune infiltrates

C Ding, R He, J Zhang, Z Dong, J Wu - Cancer Cell International, 2021 - Springer
Background Pseudogenes played important roles in tumorigenesis, while there are nearly
no reports about the expression and roles of HSPA7 in the cancer. Methods Firstly, we used …

Upregulation of HSPA1A/HSPA1B/HSPA7 and downregulation of HSPA9 were related to poor survival in colon cancer

Y Guan, X Zhu, J Liang, M Wei, S Huang… - Frontiers in oncology, 2021 - frontiersin.org
The human HSP70 family is a type of heat shock protein (HSP), consisting of 13 members
encoded by the HSPA genes. HSPs play important roles in regulating cellular responses …