(r) HDL in theranostics: how do we apply HDL's biology for precision medicine in atherosclerosis management?

K Belloso Uribe, A Benito Vicente, CA Martín Plágaro… - 2021 - addi.ehu.es
High-density lipoproteins (HDL) are key players in cholesterol metabolism homeostasis
since they are responsible for transporting excess cholesterol from peripheral tissues to the …

[PDF][PDF] biology for precision medicine in atherosclerosis management?

KB Uribe, A Benito-Vicente, C Martin, F Blanco-Vacac… - researchgate.net
High-density lipoproteins (HDL) are key players in cholesterol metabolism homeostasis
since they are responsible for transporting excess cholesterol from peripheral tissues to the …

(r) HDL in theranostics: how do we apply HDL's biology for precision medicine in atherosclerosis management?

KB Uribe, A Benito-Vicente, C Martin… - Biomaterials …, 2021 - pubs.rsc.org
High-density lipoproteins (HDL) are key players in cholesterol metabolism homeostasis
since they are responsible for transporting excess cholesterol from peripheral tissues to the …

Advances in HDL: much more than lipid transporters

S Ben-Aicha, L Badimon, G Vilahur - International Journal of Molecular …, 2020 - mdpi.com
High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

Nanotechnology for synthetic high-density lipoproteins

AJ Luthi, PC Patel, CH Ko, RK Mutharasan… - Trends in molecular …, 2010 - cell.com
Atherosclerosis is the disease mechanism responsible for coronary heart disease (CHD),
the leading cause of death worldwide. One strategy to combat atherosclerosis is to increase …

HDL functionality in reverse cholesterol transport—Challenges in translating data emerging from mouse models to human disease

M Lee-Rueckert, JC Escola-Gil, PT Kovanen - Biochimica et Biophysica …, 2016 - Elsevier
Whereas LDL-derived cholesterol accumulates in atherosclerotic lesions, HDL particles are
thought to facilitate removal of cholesterol from the lesions back to the liver thereby …

Functionalization of reconstituted hdl for theranostic in cardiovascular disease

S Jebari, KB Uribe, AB Vicente… - …, 2020 - atherosclerosis-journal.com
Methods: In vitro production of rHDL was studied by mixing apoA-1 with different lipids and
microRNA. Biophysical characterization was performed by circular dichroism, dynamic light …

High-density lipoprotein-based drug discovery for treatment of atherosclerosis

Y Du, L Wang, B Hong - Expert Opinion on Drug Discovery, 2015 - Taylor & Francis
Introduction: Although there has been great progress achieved by the use of intensive statin
therapy, the burden of atherosclerotic cardiovascular disease (CVD) remains high. This has …

A natural nano-platform: advances in drug delivery system with recombinant high-density lipoprotein

Z Xie, G Zhang, Y Meng, Y Tong, J Deng, H Li… - Chinese Chemical …, 2024 - Elsevier
Developing natural nano-platforms with high biocompatibility and natural targeting ability
represents great significance for drug delivery. High-density lipoprotein (HDL), a natural lipid …

Evaluation of reconstituted high-density lipoprotein (rHDL) as a drug delivery platform–a detailed survey of rHDL particles ranging from biophysical properties to …

JB Simonsen - Nanomedicine: Nanotechnology, Biology and Medicine, 2016 - Elsevier
During the last decade, and with increasing intensity, the potential for using reconstituted
high-density lipoprotein (rHDL) particles to deliver hydrophobic drugs to impaired cells and …