The adaptive immune response is a major determinant of the clinical outcome after SARS-
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …

Robust T cell responses have been associated with milder outcomes in many infections. T
cells also establish long-term memory pools and, as they are predominantly directed toward …

The immune response to SARS-CoV-2 is critical in controlling disease, but there is concern
that waning immunity may predispose to reinfection. We analyzed the magnitude and …

Tremendous progress has been made in understanding the role of T cell immunity in acute
and convalescent COVID-19 infection. Here, we shed light on the “known unknowns” of …

Host genetic and environmental factors including age, biological sex, diet, geographical
location, microbiome composition and metabolites converge to influence innate and …

SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …

Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2 | Nature Immunology Skip
to main content Thank you for visiting nature.com. You are using a browser version with limited …

The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …

A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Exceptional efforts have been undertaken to shed light into the biology of adaptive immune
responses to SARS-CoV-2. T cells occupy a central role in adaptive immunity to mediate …