Pharmacogenomic characterization in bipolar spectrum disorders

S Fortinguerra, V Sorrenti, P Giusti, M Zusso, A Buriani - Pharmaceutics, 2019 - mdpi.com
The holistic approach of personalized medicine, merging clinical and molecular
characteristics to tailor the diagnostic and therapeutic path to each individual, is steadily …

Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment …

AB Cuéllar-Barboza, SL McElroy, M Veldic… - International Journal of …, 2020 - Springer
Background Treatment in bipolar disorder (BD) is commonly applied as a multimodal
therapy based on decision algorithms that lack an integrative understanding of molecular …

[HTML][HTML] Pharmacogenomic aspects of bipolar disorder: an update

M Budde, D Degner, J Brockmöller… - European …, 2017 - Elsevier
The hopes for readily implementable precision medicine are high. For many complex
disorders, such as bipolar disorder, these hopes critically hinge on tangible successes in …

Pharmacogenomics of bipolar disorder

G Severino, A Squassina, M Costa, C Pisanu… - …, 2013 - Future Medicine
Bipolar disorder (BD) is a lifelong severe psychiatric condition with high morbidity, disability
and excess mortality. The longitudinal clinical trajectory of BD is significantly modified by …

[HTML][HTML] Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder

A Squassina, M Manchia… - Human genomics and …, 2010 - ncbi.nlm.nih.gov
Bipolar disorder (BD) is a chronic and often severe psychiatric illness characterized by
manic and depressive episodes. Among the most effective treatments, mood stabilizers …

The experience of bipolar disorder: a personal perspective on the impact of mood disorder symptoms

J Licinio - Molecular psychiatry, 2005 - nature.com
This is a personal perspective on bipolar disorder, entirely written by a well-informed patient
who is a successful mental heath professional. The patient prefers to remain anonymous; …

Pharmacogenomics in the treatment of mood disorders: strategies and opportunities for personalized psychiatry

AT Amare, KO Schubert, BT Baune - EPMA journal, 2017 - Springer
Personalized medicine (personalized psychiatry in a specific setting) is a new model
towards individualized care, in which knowledge from genomics and other omic pillars …

Pharmacogenomic biomarkers and their applications in psychiatry

H Kam, H Jeong - Genes, 2020 - mdpi.com
Realizing the promise of precision medicine in psychiatry is a laudable and beneficial
endeavor, since it should markedly reduce morbidity and mortality and, in effect, alleviate the …

Genetic variations associated with long-term treatment response in bipolar depression

G Anmella, S Vilches, J Espadaler-Mazo, A Murru… - Genes, 2021 - mdpi.com
Several pharmacogenetic-based decision support tools for psychoactive medication
selection are available. However, the scientific evidence of the gene-drug pairs analyzed is …

How Useful Are Pharmacogenomic Decision Support Tools for the Treatment of Bipolar Disorder?

JJ Rakofsky - Focus, 2018 - Am Psychiatric Assoc
Bipolar disorder can be challenging to treat, especially depressive episodes and ultrarapid
cycling presentations. Patients with bipolar disorder take an average of four psychotropic …