Abstract Background Drug adverse events (AEs), or called adverse drug events (ADEs), are
ranked one of the leading causes of mortality. The Ontology of Adverse Events (OAE) has …

Background Neuropathy often occurs following drug treatment such as chemotherapy.
Severe instances of neuropathy can result in cessation of life-saving chemotherapy …

A semantically coded knowledge base of adverse drug events (ADEs) with severity
information is critical for clinical decision support systems and translational research …

Background Licensed drugs may cause unexpected adverse reactions in patients, resulting
in morbidity, risk of mortality, therapy disruptions, and prolonged hospital stays. Officially …

The growing significance of bioinformatics and systems biology in drug safety research
requires a system of adverse‐event classification that goes beyond a simple vocabulary …

Compared with controlled terminologies (eg, MedDRA, CTCAE, and WHO-ART), the
community-based Ontology of Adverse Events (OAEs) has many advantages in AE …

Abstract Background Adverse drug reactions (ADRs), also called as drug adverse events
(AEs), are reported in the FDA drug labels; however, it is a big challenge to properly retrieve …

Background While the association between a drug and an adverse event (ADE) is generally
detected at the level of individual drugs, ADEs are often discussed at the class level, ie, at …

A critical issue in the usage of cancer drugs is its association with various adverse events
(AEs) in some, but not all, patients. The National Cancer Institute (NCI) Common …

Introduction A translational bioinformatics challenge exists in connecting population and
individual clinical phenotypes in various formats to biological mechanisms. The Medical …