Univariable and multivariable Mendelian randomization investigating the effects of telomere length on the risk of adverse pregnancy outcomes

X Han, T Wu, C Liu - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Numerous observational studies have revealed a correlation between telomere
length (TL) and adverse pregnancy outcomes (APOs). However, the impacts of TL on APOs …

Robust evidence supports a causal link between higher birthweight and longer telomere length: a mendelian randomization study

Z Zhang, J Zhang, K Zhang, X Ge, X Zhai - Frontiers in Genetics, 2024 - frontiersin.org
Background Observational studies have suggested a potential relationship between
birthweight and telomere length. However, the causal link between these two parameters …

The association between telomere length and blood lipids: a bidirectional two-sample Mendelian randomization study

S Yang, X Wang, Y Li, L Zhou, G Guo… - Frontiers in …, 2024 - frontiersin.org
Background Observational studies suggest an association between telomere length (TL)
and blood lipid (BL) levels. Nevertheless, the causal connections between these two traits …

Unraveling the causal association between leukocyte telomere length and infertility: A two-sample Mendelian randomization study

G An, X Zhao, C Zhao - Plos one, 2024 - journals.plos.org
Infertility is a significant challenge in modern society, and observed studies have reported
the association between telomere length and infertility. Whether this relationship is causal …

Are pregnancy and parity associated with telomere length? A systematic review

N Houminer-Klepar, S Bord, E Epel… - BMC Pregnancy and …, 2023 - Springer
Background Women's reproduction requires increased energy demands, which
consequently may lead to cellular damage and aging. Hence, Telomere Length (TL), a …

Leukocyte telomere length is associated with increased risk of endometriosis: a bidirectional two-sample Mendelian randomization study

C Bai, Z Shen, B Qiu, S Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Endometriosis (EMs) is a common gynecological disorder. Observational
studies on the relationship between leukocyte telomere length (LTL) and EMs have shown …

A Prospective study of leukocyte telomere length and risk of gestational diabetes in a multiracial cohort

Y Lin, Y Zhu, J Wu, SN Hinkle, S Rawal, J Han… - …, 2019 - journals.lww.com
Background: Short telomere length (TL), an indicator of cellular aging and oxidative stress,
has been implicated in glucose homeostasis. Additionally, studies have illustrated that the …

Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study

Y Deng, Q Li, F Zhou, G Li, J Liu, J Lv, L Li… - Frontiers in …, 2022 - frontiersin.org
Background The causal direction and magnitude of the associations between telomere
length (TL) and cardiovascular diseases (CVDs) remain uncertain due to susceptibility of …

The association of female and male infertility with telomere length

E Vasilopoulos, P Fragkiadaki… - International …, 2019 - spandidos-publications.com
Telomere length (TL) has long been associated with aging, as telomeres serve as protective
caps of chromosomes, and are thus deeply involved in the preservation of genome integrity …

Telomere length, pre-eclampsia, and gestational diabetes

EW Harville, MA Williams, C Qiu, J Mejia… - BMC research …, 2010 - Springer
Background Telomere length is a marker of cumulative damage to the cell, and has been
associated with cardiovascular disease, hypertension, and diabetes. Findings The …