The relationship between cannabis and schizophrenia: a genetically informed perspective
Abstract Background and Aims While epidemiological studies support a role for heavy, high‐
potency cannabis use on first‐episode psychosis, genetic models of causation suggest …
potency cannabis use on first‐episode psychosis, genetic models of causation suggest …
Cannabis use and risk of schizophrenia: a Mendelian randomization study
Cannabis use is observationally associated with an increased risk of schizophrenia, but
whether the relationship is causal is not known. Using a genetic approach, we took 10 …
whether the relationship is causal is not known. Using a genetic approach, we took 10 …
Associations between cannabis use, polygenic liability for schizophrenia, and cannabis-related experiences in a sample of cannabis users
EC Johnson, SMC Colbert, PW Jeffries… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypothesis Risk for cannabis use and schizophrenia is influenced
in part by genetic factors, and there is evidence that genetic risk for schizophrenia is …
in part by genetic factors, and there is evidence that genetic risk for schizophrenia is …
Genetic predisposition to schizophrenia associated with increased use of cannabis
Cannabis is the most commonly used illicit drug worldwide. With debate surrounding the
legalization and control of use, investigating its health risks has become a pressing area of …
legalization and control of use, investigating its health risks has become a pressing area of …
Genetic association between schizophrenia and cannabis use
Background and aim Previous studies have shown a relationship between schizophrenia
and cannabis use. As both traits are substantially heritable, a shared genetic liability could …
and cannabis use. As both traits are substantially heritable, a shared genetic liability could …
Assessing causality in associations between cannabis use and schizophrenia risk: a two-sample Mendelian randomization study
BackgroundObservational associations between cannabis and schizophrenia are well
documented, but ascertaining causation is more challenging. We used Mendelian …
documented, but ascertaining causation is more challenging. We used Mendelian …
Cannabis use and genetic predisposition for schizophrenia: a case-control study
BackgroundCannabis use may be a risk factor for schizophrenia. Part of this association
may be explained by genotype–environment interaction, and part of it by genotype …
may be explained by genotype–environment interaction, and part of it by genotype …
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability
Cannabis use is a heritable trait that has been associated with adverse mental health
outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to …
outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to …
Genome-wide identification of the shared genetic basis of cannabis and cigarette smoking and schizophrenia implicates NCAM1 and neuronal abnormality
Objectives Confirming the existence and composition of the shared genetic basis of
Schizophrenia and cannabis and cigarette smoking has critical values for the clinical …
Schizophrenia and cannabis and cigarette smoking has critical values for the clinical …
Genetic correlation between smoking behaviors and schizophrenia
SM Hartz, AC Horton, DB Hancock, TB Baker… - Schizophrenia …, 2018 - Elsevier
Nicotine dependence is highly comorbid with schizophrenia, and the etiology of the
comorbidity is unknown. To determine whether there is a genetic correlation of smoking …
comorbidity is unknown. To determine whether there is a genetic correlation of smoking …