Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

CA Tagge, AM Fisher, OV Minaeva… - Brain, 2018 - academic.oup.com
The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …

Concussive brain trauma in the mouse results in acute cognitive deficits and sustained impairment of axonal function

JA Creed, AM DiLeonardi, DP Fox… - Journal of …, 2011 - liebertpub.com
Concussive brain injury (CBI) accounts for approximately 75% of all brain-injured people in
the United States each year and is particularly prevalent in contact sports. Concussion is the …

Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts

AC McKee, TD Stein, BR Huber, JF Crary… - Acta …, 2023 - Springer
Over the last 17 years, there has been a remarkable increase in scientific research
concerning chronic traumatic encephalopathy (CTE). Since the publication of NINDS–NIBIB …

The pathophysiology of concussion

MC Choe - Current pain and headache reports, 2016 - Springer
Concussion is a significant issue in medicine and the media today. With growing interest on
the long-term effects of sports participation, it is important to understand what occurs in the …

Magnitude of head impact exposures in individual collegiate football players

JJ Crisco, BJ Wilcox, JT Machan… - Journal of applied …, 2012 - journals.humankinetics.com
The purpose of this study was to quantify the severity of head impacts sustained by
individual collegiate football players and to investigate differences between impacts …

Traumatic brain injury (TBI) in collision sports: Possible mechanisms of transformation into chronic traumatic encephalopathy (CTE)

TB VanItallie - Metabolism, 2019 - Elsevier
Traumatic brain injury (TBI) is a leading cause of death and disability, contributing to~ 30%
of all injury-related deaths in the US. TBI occurs when a force transmitted to the head causes …

A modified controlled cortical impact technique to model mild traumatic brain injury mechanics in mice

YC Chen, H Mao, KH Yang, T Abel… - Frontiers in neurology, 2014 - frontiersin.org
For the past 25 years, controlled cortical impact (CCI) has been a useful tool in traumatic
brain injury (TBI) research, creating injury patterns that includes primary contusion, neuronal …

[HTML][HTML] The neuropathology and neurobiology of traumatic brain injury

K Blennow, J Hardy, H Zetterberg - Neuron, 2012 - cell.com
The acute and long-term consequences of traumatic brain injury (TBI) have received
increased attention in recent years. In this Review, we discuss the neuropathology and …

Long-term cognitive and neuropsychiatric consequences of repetitive concussion and head-impact exposure

T McAllister, M McCrea - Journal of athletic training, 2017 - meridian.allenpress.com
Initially, interest in sport-related concussion arose from the premise that the study of athletes
engaged in sports associated with high rates of concussion could provide insight into the …

The biomechanical signature of loss of consciousness: computational modelling of elite athlete head injuries

KA Zimmerman, J Cournoyer, H Lai, SB Snider… - Brain, 2023 - academic.oup.com
Sports related head injuries can cause transient neurological events including loss of
consciousness and dystonic posturing. However, it is unknown why head impacts that …