artemis: A Multicenter, Open-Label, Single-Arm, Phase II Study to Evaluate the Efficacy and Safety of first-line Carboplatin/Paclitaxel/Lenvatinib/Pembrolizumab …

Y Okuma, S Nomura, J Sakakibara-Konishi… - Clinical Lung Cancer, 2024 - Elsevier
Background: Thymic carcinoma is a rare cancer with an aggressive clinical presentation and
no organotypic symptoms. Despite using platinum-based chemotherapy as first-line …

[HTML][HTML] Long-term follow-up and exploratory analysis of lenvatinib in patients with metastatic or recurrent thymic carcinoma: Results from the multicenter, phase 2 …

S Niho, J Sato, M Satouchi, S Itoh, Y Okuma… - Lung Cancer, 2024 - Elsevier
Objectives The main objective of this report was to detail the long-term follow-up data from
the REMORA study, which investigated the safety and efficacy of lenvatinib in patients with …

[HTML][HTML] Chemotherapy with paclitaxel plus carboplatin for relapsed advanced thymic carcinoma

Z Song - Journal of Thoracic Disease, 2014 - ncbi.nlm.nih.gov
Objective For rarity of thymic carcinoma, no definitive chemotherapeutic regimen has been
established in second-or further-line settings. The aim of this study was to evaluate the …

[HTML][HTML] Durable anti-tumor activity of the multi-targeted inhibitor lenvatinib in patients with advanced or metastatic thymic carcinoma: Preliminary results from a …

S Itoh, M Satouchi, J Sato, Y Okuma, S Niho… - Annals of …, 2019 - Elsevier
Background Thymic carcinoma is a rare malignant disease. Standard treatments have not
been established for patients with advanced or metastatic thymic carcinoma previously …

Salvage chemotherapy in patients with previously treated thymic carcinoma

K Kaira, H Imai, O Yamaguchi, A Mouri, H Kagamu - Cancers, 2021 - mdpi.com
Simple Summary Thymic carcinoma is identified as thoracic neoplasm having low sensitivity
to systemic chemotherapy. As first-line setting, platinum-based chemotherapy is …

Characteristics and outcome of systemic treatment for metastatic or unresectable thymic carcinoma: A single institution experience

IW Ho, YL Pan, JI Lai, CY Liu - Thoracic Cancer, 2024 - Wiley Online Library
Background Thymic carcinoma is a rare disease with an incidence of around 0.5 cases per
million with a poor prognosis. The aim of this study was to assess patient outcomes with …

Optimal first‐line treatment for advanced thymic carcinoma

X Yang, M Zhuo, A Shi, S Yang, Z Wang, M Wu… - Thoracic …, 2019 - Wiley Online Library
Background Thymic carcinomas (TCs) are rare aggressive tumors with no standard first‐line
treatment. This study was conducted to determine the optimal chemotherapy regimen for …

Efficacy of chemotherapy with carboplatin and paclitaxel for unresectable thymic carcinoma

S Igawa, H Murakami, T Takahashi, Y Nakamura… - Lung Cancer, 2010 - Elsevier
BACKGROUND: Thymic carcinoma is a very rarely encountered neoplasm and no optimal
chemotherapeutic regimen has been established yet. METHODS: The records of previously …

Docetaxel for platinum-refractory advanced thymic carcinoma

N Watanabe, S Umemura, S Niho… - Japanese Journal of …, 2015 - academic.oup.com
Objective Thymic carcinoma is a rare mediastinal neoplasm. While platinum-based
chemotherapy has been reported to be effective for advanced thymic carcinoma in a first-line …

[HTML][HTML] Efficacy and safety of treatments for advanced thymic carcinoma after failure of first-line platinum-based chemotherapy: a systematic literature review and meta …

A Arunachalam, I Zhang, B Zhao, AM Frederickson… - Lung Cancer, 2023 - Elsevier
Thymic carcinoma (TC) is a rare cancer and patients failing initial chemotherapy
(relapse/refractory) face limited therapeutic options given no approved options or consensus …