Interleukins-1,-4,-6,-10, tumor necrosis factor, transforming growth factor-β, FAS, and mannose-binding protein C gene polymorphisms in Australian women: risk of …

MF Annells, PH Hart, CG Mullighan, SL Heatley… - American journal of …, 2004 - Elsevier
OBJECTIVE: The purpose of this study was to examine the relationship between preterm
birth and 22 single nucleotide polymorphisms in genes that encode cytokines and mediators …

Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birth

MV Hollegaard, J Grove, P Thorsen… - Acta obstetricia et …, 2008 - Taylor & Francis
Objective. To investigate the relation between 19 selected single nucleotide polymorphisms
in three cytokine genes, tumor necrosis factor alpha (TNFA), interleukin 1-beta (IL1B) and …

Association of genetic variants, ethnicity and preterm birth with amniotic fluid cytokine concentrations

R Menon, SJ Fortunato… - Annals of human …, 2010 - Wiley Online Library
We examined the association of 166 single nucleotide polymorphisms (SNPs) in cytokines
and cytokine related genes with cytokine concentrations (IL‐1β, IL‐8, and IL‐10) in the …

Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of …

BRA Ramos, ND Mendes, AA Tanikawa… - BMC Pregnancy and …, 2016 - Springer
Background A genetic predisposition to Preterm Labor (PTL) and Preterm Premature
Rupture of Membranes (PPROM) has been suggested; however the relevance of …

Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms

SAM Engel, HC Erichsen, DA Savitz, J Thorp… - …, 2005 - journals.lww.com
Background: Preliminary data suggest that common genetic variation in immune response
genes can contribute to the risk for spontaneous preterm birth and possibly small-for …

Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants

DR Velez, S Fortunato, P Thorsen, SJ Lombardi… - American journal of …, 2009 - Elsevier
OBJECTIVE: The objective of the study was to study the genetic risk factors of spontaneous
preterm birth (PTB) in African Americans. STUDY DESIGN: Case-control analyses were …

Interleukin-6 promoter− 174 polymorphism and spontaneous preterm birth

HN Simhan, MA Krohn, JM Roberts, A Zeevi… - American journal of …, 2003 - Elsevier
OBJECTIVE: We assessed the relationship between interleukin-6 (IL-6) promoter− 174
polymorphism and spontaneous preterm birth (sPTB) less than 34 weeks and the …

Ethnic differences of polymorphisms in cytokine and innate immune system genes in pregnant women

DP Nguyen, M Genc, S Vardhana, O Babula… - Obstetrics & …, 2004 - journals.lww.com
OBJECTIVE: Investigations of the possible role of polymorphic genes in pregnancy outcome
may be influenced by ethnic variations in genotype or allele frequencies. Differences in …

Risk of small-for-gestational age is associated with common anti-inflammatory cytokine polymorphisms

SAM Engel, AF Olshan, DA Savitz, J Thorp… - …, 2005 - journals.lww.com
Background: Anti-inflammatory cytokines play a key role in pregnancy maintenance. Genetic
variation in anti-inflammatory cytokines could influence a woman's risk of adverse …

Polymorphism in the interleukin-1 gene complex and spontaneous preterm delivery

MR Genç, S Gerber, M Nesin, SS Witkin - American journal of obstetrics and …, 2002 - Elsevier
Objective: We examined the association between preterm delivery and polymorphisms at
position+ 3953 of the interleukin-1β gene (IL1B+ 3953) and in intron 2 of the interleukin-1 …