[HTML][HTML] Mechanisms implicated in the contralateral effect in the central nervous system after unilateral injury: Focus on the visual system

F Lucas-Ruiz, C Galindo-Romero… - Neural Regeneration …, 2021 - journals.lww.com
The retina, as part of the central nervous system is an ideal model to study the response of
neurons to injury and disease and to test new treatments. During the last decade is …

Interretinal transduction of injury signals after unilateral optic nerve crush

T Macharadze, J Goldschmidt, M Marunde… - …, 2009 - journals.lww.com
In this study, we report that partial unilateral optic nerve crush in the rat affects the number of
retinal ganglion cells of the contralateral eye still in continuity with the ipsilateral superior …

Unilateral injury to the adult rat optic nerve causes multiple cellular responses in the contralateral site

N Bodeutsch, H Siebert, C Dermon… - Journal of …, 1999 - Wiley Online Library
This study was undertaken to examine whether unilateral injury to one optic nerve (ON)
elicits a response in the microglia, neuroglia and ganglion cells of the retina and ON of the …

[HTML][HTML] Neuronal death in the contralateral un-injured retina after unilateral axotomy: Role of microglial cells

F Lucas-Ruiz, C Galindo-Romero… - International Journal of …, 2019 - mdpi.com
For years it has been known that unilateral optic nerve lesions induce a bilateral response
that causes an inflammatory and microglial response in the contralateral un-injured retinas …

Unilateral optic nerve crush induces bilateral retinal glial cell proliferation

L Panagis, S Thanos, D Fischer… - European Journal of …, 2005 - Wiley Online Library
The post‐injury responses of retinal ganglion cells elicit a number of glial reactions which
have not been completely understood. The bilateral pattern of non‐neuronal retinal cell …

Bilateral Retinal Responses after Traumatic Injury of One Eye in Mice: A Histopathologic and Immunohistochemical Study

DT Yew, QD Yang, NY Mak, CYW Au, WWY Li… - Ophthalmic …, 1990 - karger.com
Abstract Iron wires (0.3 mm in diameter and 1.2 mm in length) were lodged in the left eyes of
albino mice. 4 weeks after the experiment, the left and right eyes were sectioned and …

Neuroprotection in ophthalmology: a review

Y Barkana, M Belkin - Brain research bulletin, 2004 - Elsevier
Evidence has accumulated that damaged neural cells may not inevitably degenerate, and
that in vivo cells which are not directly injured by an insult may be adversely affected by …

[HTML][HTML] Axonal injuries cast long shadows: Long term glial activation in injured and contralateral retinas after unilateral axotomy

MJ González-Riquelme, C Galindo-Romero… - International Journal of …, 2021 - mdpi.com
Background: To analyze the course of microglial and macroglial activation in injured and
contralateral retinas after unilateral optic nerve crush (ONC). Methods: The left optic nerve of …

[HTML][HTML] Unilateral corneal insult also alters sensory nerve activity in the contralateral eye

C Luna, S Quirce, A Aracil-Marco, C Belmonte… - Frontiers in …, 2021 - frontiersin.org
After the unilateral inflammation or nerve lesion of the ocular surface, the ipsilateral corneal
sensory nerve activity is activated and sensitized, evoking ocular discomfort, irritation, and …

[HTML][HTML] Traumatic optic neuropathy‑a contralateral finding: A case report

M Kyncl, J Lestak, J Tintera… - Experimental and …, 2019 - spandidos-publications.com
The present study demonstrates alterations of the contralateral side optic tract to an optic
nerve traumatic lesion. Visual acuity of the right eye following Traumatic optic neuropathy …