[HTML][HTML] Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

A Fernández-Castañeda, P Lu, AC Geraghty, E Song… - Cell, 2022 - cell.com
COVID survivors frequently experience lingering neurological symptoms that resemble
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …

[HTML][HTML] Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain

A Fernández-Castañeda, P Lu, AC Geraghty, E Song… - BioRxiv, 2022 - ncbi.nlm.nih.gov
Abstract Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
infection frequently experience lingering neurological symptoms, including impairment in …

COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis

AL Soung, A Vanderheiden, AS Nordvig, CA Sissoko… - Brain, 2022 - academic.oup.com
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
associated with acute and postacute cognitive and neuropsychiatric symptoms including …

SARS-CoV-2 infection of microglia elicits proinflammatory activation and apoptotic cell death

GU Jeong, J Lyu, KD Kim, YC Chung… - Microbiology …, 2022 - Am Soc Microbiol
Accumulating evidence suggests that severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection causes various neurological symptoms in patients with coronavirus …

[HTML][HTML] SARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability

F Crunfli, VC Carregari, FP Veras, PH Vendramini… - MedRxiv, 2021 - medrxiv.org
One increasingly documented tendency of COVID-19 patients is to exhibit neuropsychiatric
and neurological symptoms. Here we found that anxiety and cognitive impairment are …

Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model

C Käufer, CS Schreiber, AS Hartke, I Denden… - …, 2022 - thelancet.com
Background Neurological symptoms such as cognitive decline and depression contribute
substantially to post-COVID-19 syndrome, defined as lasting symptoms several weeks after …

[HTML][HTML] Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

M Schwabenland, H Salié, J Tanevski, S Killmer… - Immunity, 2021 - cell.com
COVID-19 can cause severe neurological symptoms, but the underlying pathophysiological
mechanisms are unclear. Here, we interrogated the brain stems and olfactory bulbs in …

Inflammatory response leads to neuronal death in human post-mortem cerebral cortex in patients with COVID-19

ME Boroujeni, L Simani, HAR Bluyssen… - ACS chemical …, 2021 - ACS Publications
The recent coronavirus disease of 2019 (COVID-19) pandemic has adversely affected
people worldwide. A growing body of literature suggests the neurological complications and …

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early-and late-phase COVID-19

J Radke, J Meinhardt, T Aschman, RL Chua… - Nature …, 2024 - nature.com
Neurological symptoms, including cognitive impairment and fatigue, can occur in both the
acute infection phase of coronavirus disease 2019 (COVID-19) and at later stages, yet the …

SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19

D Beckman, A Bonillas, GB Diniz, S Ott, JW Roh… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of
coronavirus disease 2019 (COVID-19), can induce a plethora of neurological complications …