Exploring Leishmania secretory proteins to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach
Visceral leishmaniasis (VL) is a fatal form of leishmaniasis which affects 70 countries,
worldwide. Increasing drug resistance, HIV co-infection, and poor health system require …
worldwide. Increasing drug resistance, HIV co-infection, and poor health system require …
Design of a multi-epitope subunit vaccine for immune-protection against Leishmania parasite
Visceral Leishmaniasis (VL) is an insect-borne neglected disease caused by the protozoan
parasite Leishmania donovani. In the absence of a commercial vaccine against VL …
parasite Leishmania donovani. In the absence of a commercial vaccine against VL …
Immunoinformatics-aided design of a potential multi-epitope peptide vaccine against Leishmania infantum
Visceral leishmaniasis (VL) or kala-azar, the most severe form of the disease, is endemic in
more than eighty countries across the world. To date, there is no approved vaccine against …
more than eighty countries across the world. To date, there is no approved vaccine against …
Vaccinomics-based next-generation multi-epitope chimeric vaccine models prediction against Leishmania tropica - a hierarchical subtractive proteomics and …
Leishmania tropica is a vector-borne parasitic protozoa that is the leading cause of
leishmaniasis throughout the global tropics and subtropics. L. tropica is a multidrug-resistant …
leishmaniasis throughout the global tropics and subtropics. L. tropica is a multidrug-resistant …
Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein
Malaria fever has been pervasive for quite a while in tropical developing regions causing
high morbidity and mortality. The causal organism is a protozoan parasite of genus …
high morbidity and mortality. The causal organism is a protozoan parasite of genus …
Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins
M Agallou, E Athanasiou, O Koutsoni… - Frontiers in …, 2014 - frontiersin.org
Leishmaniasis is a significant worldwide health problem for which no vaccine exists.
Activation of CD4+ and CD8+ T cells is crucial for the generation of protective immunity …
Activation of CD4+ and CD8+ T cells is crucial for the generation of protective immunity …
Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection
Dengue is considered as a major health issue which causes a number of deaths worldwide
each year; tropical countries are majorly affected by dengue outbreaks. It is considered as …
each year; tropical countries are majorly affected by dengue outbreaks. It is considered as …
Immunoinformatics Aided Design and In-Vivo Validation of a Cross-Reactive Peptide Based Multi-Epitope Vaccine Targeting Multiple Serotypes of Dengue Virus
Dengue virus (DENV) is an arboviral disease affecting more than 400 million people
annually. Only a single vaccine formulation is available commercially and many others are …
annually. Only a single vaccine formulation is available commercially and many others are …
Immunoinformatics approaches to design a novel multi-epitope subunit vaccine against HIV infection
The end goal of HIV vaccine designing requires novel strategies to elicit a strong humoral
and cell-mediated immune response. The emergence of drug resistance and the …
and cell-mediated immune response. The emergence of drug resistance and the …
Immunoinformatics designed T cell multi epitope dengue peptide vaccine derived from non structural proteome
Dengue viral disease has been reported as an Aedes aegypti mosquito-borne human
disease and causing a severe global public health concern. In this study, immunoinformatics …
disease and causing a severe global public health concern. In this study, immunoinformatics …