The crucial roles that glycans play in biological systems are determined by their structures.
However, the analysis of glycan structures still has numerous bottlenecks due to their …

Glycan is a crucial class of biological macromolecules with important biological functions.
Functional groups determine the chemical properties of glycans, which further affect their …

Structural complexity of glycans derived from the diversities in composition, linage,
configuration, and branching considerably complicates structural analysis. Nanopore-based …

Saccharides are not only the basic constituents and nutrients of living organisms, but also
participate in various life activities, and play important roles in cell recognition, immune …

Glycosaminoglycans are highly anionic functional polysaccharides with information content
in their structure that plays a major role in the communication between the cell and the …

A nanopore can be fairly—but uncharitably—described as simply a nanofluidic channel
through a thin membrane. Even this simple structural description holds utility and underpins …

Saccharides play critical roles in many forms of cellular activities. Saccharide structures are
however complicated and similar, setting a technical hurdle for direct identification …

Glycosaminoglycans are biologically active anionic carbohydrates that are among the most
challenging biopolymers with regards to their structural analysis and functional assessment …

Glycosaminoglycans (GAGs) are a class of polysaccharides with potent biological activities.
Due to their complex and heterogeneous composition, varied charge, polydispersity, and …

The rapid progress in nanopore sensing has sparked interest in protein sequencing. Despite
recent notable advancements in amino acid recognition using nanopores, chemical …